ID A0A2U3VKB4_ODORO Unreviewed; 197 AA.
AC A0A2U3VKB4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=LOW QUALITY PROTEIN: neurturin {ECO:0000313|RefSeq:XP_004395352.1};
GN Name=NRTN {ECO:0000313|RefSeq:XP_004395352.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004395352.1};
RN [1] {ECO:0000313|RefSeq:XP_004395352.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TGF-beta family. GDNF subfamily.
CC {ECO:0000256|ARBA:ARBA00009832}.
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DR RefSeq; XP_004395352.1; XM_004395295.2.
DR STRING; 9708.A0A2U3VKB4; -.
DR GeneID; 101365865; -.
DR KEGG; oro:101365865; -.
DR CTD; 4902; -.
DR InParanoid; A0A2U3VKB4; -.
DR OrthoDB; 4316464at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0030116; F:glial cell-derived neurotrophic factor receptor binding; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0030971; F:receptor tyrosine kinase binding; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd19383; TGF_beta_Neurturin; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR043401; GDNF_fam.
DR InterPro; IPR001839; TGF-b_C.
DR PANTHER; PTHR12173; GDNF SUBFAMILY OF TGF-BETA FAMILY; 1.
DR PANTHER; PTHR12173:SF3; NEURTURIN; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340}.
FT DOMAIN 82..197
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 73..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..98
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 197 AA; 22289 MW; 3D4B1E983AD6C001 CRC64;
MQRWKAAALA SVLCSSVLSI WMCRDGLLLS HHLGPSLTPL RRPPRTLDAR IVRLAQYRAL
LQGAPDAVEL RQLTPWAGRP PRPRRRAGPR RRRARARSGT RPCGLRELEV RVSELGLGYA
SDEXALFRYC AGAWGAAARV YDLGLRRLRQ GQCVRRQRVR AQPCCRPTAY EDEVSFLDAH
SRYHTVHELS ARECACV
//
