ID A0A2U3VKG7_ODORO Unreviewed; 385 AA.
AC A0A2U3VKG7;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Sphingosine 1-phosphate receptor 4 isoform X1 {ECO:0000313|RefSeq:XP_004395421.1};
GN Name=S1PR4 {ECO:0000313|RefSeq:XP_004395421.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004395421.1};
RN [1] {ECO:0000313|RefSeq:XP_004395421.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_004395421.1; XM_004395364.1.
DR AlphaFoldDB; A0A2U3VKG7; -.
DR STRING; 9708.A0A2U3VKG7; -.
DR GeneID; 101384584; -.
DR KEGG; oro:101384584; -.
DR CTD; 8698; -.
DR InParanoid; A0A2U3VKG7; -.
DR OrthoDB; 4607247at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0038036; F:sphingosine-1-phosphate receptor activity; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR004064; EDG6_rcpt.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR004061; S1P_rcpt.
DR PANTHER; PTHR22750; G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR22750:SF13; SPHINGOSINE 1-PHOSPHATE RECEPTOR 4; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR01526; EDG6RECEPTOR.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR01523; S1PRECEPTOR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_004395421.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW Transducer {ECO:0000256|ARBA:ARBA00023040};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 64..308
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 385 AA; 42009 MW; 7F4C939B6BF3F8E3 CRC64;
MNTTGPPAEA PESCQQLVAS GHSRLIVLHY NHSGRLAGRG GPEEGSLGVL RGIFVAVSCL
VVLENLLVLV AIVTHMRSRR WVYYCLVNIT LSDLLTGVAY LANVLLSGAR TFHLAPAHWF
LREGLLFMAL AASTFSLLFT AGERFATMVR PVAESGASKR GRVYGFIGLC WLLAALLGLL
PLLGWNCVCA FQRCSSLLPL YSKAYILFCV GVFACILAAI MALYGAIFRV VRANGQKAPR
PPSRRKARRL LKTVLMILVA FVVCWGPLFG LLLADVFSST DWAQEYLRGM DWILALAVLN
SAVNPLIYSF RSREVCQAVL AFLCCGCLRL GLQGPRDCLA QVSEAHSGAS TTDSSLRPRD
SFRGSRSLSF RMREPLTSIS SVRSV
//
