ID A0A2U3VKV2_ODORO Unreviewed; 419 AA.
AC A0A2U3VKV2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=ETS translocation variant 1 isoform X4 {ECO:0000313|RefSeq:XP_004395586.1};
GN Name=ETV1 {ECO:0000313|RefSeq:XP_004395586.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004395586.1};
RN [1] {ECO:0000313|RefSeq:XP_004395586.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_004395586.1; XM_004395529.2.
DR AlphaFoldDB; A0A2U3VKV2; -.
DR GeneID; 101384303; -.
DR CTD; 2115; -.
DR OrthoDB; 3915960at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR006715; ETS_PEA3_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF196; ETS TRANSLOCATION VARIANT 1; 1.
DR Pfam; PF00178; Ets; 1.
DR Pfam; PF04621; ETS_PEA3_N; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340}.
FT DOMAIN 277..357
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 70..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 419 AA; 48133 MW; 386578129E8CCC96 CRC64;
MLQDLSASVF FPPCSQHRTL VAFHGLPLKI KKEPHSPCSE LGSACSQEQP FKFSYGEKCL
YNVSAYDQKP QVGMRPSNPP TPSSTPVSPL HHASPNSTHT PKPDRAFPAH LPPSQPIQDS
SYPMDHRFRR QLSEPCNSFP PLPTMPREGR PMYQRQMSEP NIPFPPQGFK QEYHDPVYEH
NTMVGGAAGQ SFPPPLMIKQ EPRDFAYDSE VPSCHSIYMR QEGFLAHPSR TEGCMFEKGP
RQFYDDTCVV PEKFDGDIKQ EPGMYREGPT YQRRGSLQLW QFLVALLDDP SNSHFIAWTG
RGMEFKLIEP EEVARRWGIQ KNRPAMNYDK LSRSLRYYYE KGIMQKVAGE RYVYKFVCDP
EALFSMAFPD NQRPLLKTDM ERHINEEDTV PLSHFDESMA YMPEGGCCNP HPYNEAYVY
//
