ID   A0A2U3VUH2_ODORO        Unreviewed;       624 AA.
AC   A0A2U3VUH2;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Kelch-like ECH-associated protein 1 {ECO:0000256|ARBA:ARBA00018407};
GN   Name=KEAP1 {ECO:0000313|RefSeq:XP_004398925.1};
OS   Odobenus rosmarus divergens (Pacific walrus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC   Odobenus.
OX   NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004398925.1};
RN   [1] {ECO:0000313|RefSeq:XP_004398925.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the KEAP1 family.
CC       {ECO:0000256|ARBA:ARBA00005288}.
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DR   RefSeq; XP_004398925.1; XM_004398868.2.
DR   RefSeq; XP_012417290.1; XM_012561836.1.
DR   AlphaFoldDB; A0A2U3VUH2; -.
DR   STRING; 9708.A0A2U3VUH2; -.
DR   GeneID; 101378046; -.
DR   KEGG; oro:101378046; -.
DR   CTD; 9817; -.
DR   InParanoid; A0A2U3VUH2; -.
DR   OrthoDB; 5472491at2759; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000245340; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0070887; P:cellular response to chemical stimulus; IEA:UniProt.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   CDD; cd18458; BACK_KLHL19_KEAP1; 1.
DR   CDD; cd18248; BTB_POZ_KLHL19_KEAP1; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR047098; KEAP1_BACK.
DR   InterPro; IPR030563; KEAP1_BTB_POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR24412:SF35; ACTIN-BINDING PROTEIN IPP; 1.
DR   PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 6.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF117281; Kelch motif; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   3: Inferred from homology;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ   SEQUENCE   624 AA;  69899 MW;  581FE0918D8E7C0E CRC64;
     MQPEPRLSGA GARTRFLPLR SQRPEGAGDT VMYASTECKA EVTPSQHGNR TFSYTLEDHT
     KQAFGIMNEL RLSQQLCDVT LQVKYEDAPA AQFMAHKVVL ASSSPVFKAM FTNGLREQGM
     EVVSIEGIHP KVMERLIEFA YTASISMGEK CVLHVMNGAV MYQIDSVVRA CSDFLVQQLD
     PSNAIGIANF AEQIGCAELH QRAREYIYMH FGEVAKQEEF FNLSHCQLVT LISRDDLNVR
     CESEVFHACI NWVKYDCEQR RFYVQALLRA VRCHSLTPHF LQMQLQKCEI LQSDSRCKDY
     LVKIFQELTL HKPTQVMPCR APKVGRLIYT AGGYFRQSLS YLEAYNPSDG TWLRLADLQV
     PRSGLAGCVV GGLLYAVGGR NNSPDGNTDS NALDCYNPMT NQWSPCAPMS VPRNRIGVGV
     IDGYIYAVGG SHGCIHHNSV ERYEPERDEW HLVAPMLTRR IGVGVAVLNR LLYAVGGFDG
     TNRLNSAECY YPERNEWRMI TPMNTIRSGA GVCVLHNCIY AAGGYDGQDQ LNSVERYDVE
     TETWSFVAPM KHRRSALGIT VHQGRIYVLG GYDGHTFLDS VECYDPDTDT WSEVTHMTSG
     RSGVGVAVTM EPCRKQIDQQ NCTC
//