ID A0A2U3VZK2_ODORO Unreviewed; 593 AA.
AC A0A2U3VZK2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Neuronal PAS domain-containing protein 1 {ECO:0000313|RefSeq:XP_004400992.1, ECO:0000313|RefSeq:XP_004400993.1};
GN Name=NPAS1 {ECO:0000313|RefSeq:XP_004400992.1,
GN ECO:0000313|RefSeq:XP_004400993.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004400993.1};
RN [1] {ECO:0000313|RefSeq:XP_004400992.1, ECO:0000313|RefSeq:XP_004400993.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_004400992.1; XM_004400935.1.
DR RefSeq; XP_004400993.1; XM_004400936.1.
DR STRING; 9708.A0A2U3VZK2; -.
DR GeneID; 101368531; -.
DR KEGG; oro:101368531; -.
DR CTD; 4861; -.
DR OrthoDB; 5396877at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd19731; bHLH-PAS_NPAS1_PASD5; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR23043; HYPOXIA-INDUCIBLE FACTOR 1 ALPHA; 1.
DR PANTHER; PTHR23043:SF25; NEURONAL PAS DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000245340}.
FT DOMAIN 45..98
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 141..198
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 199..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 427..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..490
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 593 AA; 63322 MW; 489534F2C240B3A8 CRC64;
MAAPYPSSGG GGEVKCGGGR GRSVPWDFLP GLVVKAPPGP CLQAQRKEKS RNAARSRRGK
ENLEFFELAK LLPLPGAISS QLDKASIVRL SVTYLRLRRF AALGAPPWGL RASGPPAGLA
PGHRGPVALV SEVFEQHLGG HILQSLDGFV FALNQEGKFL YISETVSIYL GLSQVELTGS
SVFDYIHPGD HSEVLEQLGL RAPTPGPPTP PSVPSSSSSS SSSSLADTPE IEASAAEVPP
FSRVQERSFF IRMKSTLTKR GLHVKASGYK VIHVTGRLRA RSLGLVALGH TLPPAPLAEL
PLHGHMIVFR LSLGLTILAC ESRVSDHMDL GPSELVGRSC YQFVHGQDAA RIRQSHLDLL
DKGQVMTGYY RWLQRAGGFV WLQSVATVAV SGKSPGERHV LWVSYVLSQA EGGQTPLDAF
QLPASVACED ASSPEPEPTE PEPPVEGKQA APLDKDEAPQ SRGKRIKVEP RPGDAKDPED
GGDEEPPGHP ALPRPEFTSV IRAGALKQDL VRPWGLGPPG DPPPSLLHAG FLPPVVRGLC
TPGTIRYGPA ELGLMYPHLQ RLGPGPTLPE AFYPPLGLSY PGPTGTRVQR KGD
//
