ID   A0A2U3VZN2_ODORO        Unreviewed;       849 AA.
AC   A0A2U3VZN2;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Echinoderm microtubule-associated protein-like 2 isoform X1 {ECO:0000313|RefSeq:XP_004401024.1};
GN   Name=EML2 {ECO:0000313|RefSeq:XP_004401024.1};
OS   Odobenus rosmarus divergens (Pacific walrus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC   Odobenus.
OX   NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004401024.1};
RN   [1] {ECO:0000313|RefSeq:XP_004401024.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC       {ECO:0000256|ARBA:ARBA00006489}.
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DR   RefSeq; XP_004401024.1; XM_004400967.1.
DR   AlphaFoldDB; A0A2U3VZN2; -.
DR   STRING; 9708.A0A2U3VZN2; -.
DR   GeneID; 101377108; -.
DR   KEGG; oro:101377108; -.
DR   CTD; 24139; -.
DR   InParanoid; A0A2U3VZN2; -.
DR   OrthoDB; 2959353at2759; -.
DR   Proteomes; UP000245340; Unplaced.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   CDD; cd21948; TD_EMAP2; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR005108; HELP.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR13720:SF50; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2; 1.
DR   PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR   Pfam; PF03451; HELP; 1.
DR   Pfam; PF00400; WD40; 4.
DR   SMART; SM00320; WD40; 11.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN          222..292
FT                   /note="HELP"
FT                   /evidence="ECO:0000259|Pfam:PF03451"
FT   REPEAT          490..521
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          573..614
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          656..697
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          702..743
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          814..849
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          138..204
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          73..114
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   849 AA;  91626 MW;  425E24E0119F94D7 CRC64;
     MLERRALLWQ REAGPGGGDR AQAGAGGAGG GCGGAMAERG PAFCGLYDTS SLLQYCNDDN
     LSGTSGMEVD DRVSALEQRL QLQEDELAVL KAALADALRR LRACEEQGAA LRARGTPKGR
     APPRLGTTAS VCQLLKGLPT RTPLNGAGPP RRVGGYATSP SSPKKEGTSG RSARRYLSPE
     RLASVRREDP RSRTTSSSSN CSAKKEGKTK EVIFSVEEGS VKMFLRGRPV PMLIPDELAP
     TYSLDTRSEL PSNRLKLDWV HGYRGRDCRA NLYLLPTGEI VYFVASVAVL YSVEEQRQRH
     YLGHNDDIKC LAVHPDMVTI ATGQVAGTTK EGKPLPPHVR IWDSVSLSTL HVLGLGVFDR
     AVCCVGFSKS NGGNLLCAVD ESNDHMLSVW DWAKEAKVVD SKCSNEAVLV ATFHPTDPTL
     LITCGKSHIY FWSLEAGSLS KRQGLFEKHE KPKYVLCVTF LEGGDVITGD SGGNLYVWGK
     GGNRITQSVL GAHDGGVFGL CALRDGTLVS GGGRDRRVVL WGSDYSKLQE VEVPEDFGPV
     RTVAEGRGDT LYVGTTRNSI LQGSVHTGFS LLVQGHVEEL WGLATHPSRA QFVTCGQDKL
     VHLWSAESHQ PLWSRIIEDP ACSAGFHPSG SVLAVGTVTG RWLLLDTETH DLVAIHTDGN
     EQISVVSFSP DGAYLTVGSH DNLVYVYTVD QGGRKVSRLG KCSGHSSFIT HLDWAQDSSC
     FVTNSGDYEI LYWDPATCKQ ITSADAVRNM EWATATCVLG FGVFGIWSEG ADGTDINAVA
     RSHDGKLLAS ADDFGKVHLF SYPCCQPRAL SHKYGGHSSH VTNVAFLWDD SVALTTGGKD
     TSVLQWRVV
//