ID A0A2U3W1R8_ODORO Unreviewed; 597 AA.
AC A0A2U3W1R8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Nephronectin isoform X3 {ECO:0000313|RefSeq:XP_004401940.1};
GN Name=NPNT {ECO:0000313|RefSeq:XP_004401940.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004401940.1};
RN [1] {ECO:0000313|RefSeq:XP_004401940.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the nephronectin family.
CC {ECO:0000256|ARBA:ARBA00009738}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_004401940.1; XM_004401883.2.
DR AlphaFoldDB; A0A2U3W1R8; -.
DR GeneID; 101380598; -.
DR CTD; 255743; -.
DR OrthoDB; 19806at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd06263; MAM; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR000998; MAM_dom.
DR PANTHER; PTHR24050:SF19; NEPHRONECTIN; 1.
DR PANTHER; PTHR24050; PA14 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF12947; EGF_3; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF00629; MAM; 1.
DR SMART; SM00181; EGF; 5.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM00137; MAM; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 3.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 3.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS50060; MAM_2; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..597
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015583350"
FT DOMAIN 120..159
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 200..244
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 245..285
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 447..590
FT /note="MAM"
FT /evidence="ECO:0000259|PROSITE:PS50060"
FT REGION 329..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..367
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 597 AA; 65579 MW; FF1716FE46967B56 CRC64;
MDFLLALVLG SSLCLQAAAE FDVRWPRQIV SSIGLCRYGG RIDCCWGWAR RSWGQCQPVC
RPQCKHGECI GPDKCKCHPG YAGKTCSQDE HFYPTPLDQG SEQPLFQPLD HQATSLPSRD
LNECGLKPRP CKHRCMNTYG SYKCYCLNGY MLMPDGSCSS ALTCSMANCQ YGCDVVKGQI
RCQCPSPGLQ LAPDGRTCVD VDECATGSAS CPRFRQCVNT FGSYICKCQK GFDLMYIGGK
YQCHDIDECS LGQYHCSRFA RCYNVHGSYK CQCKDGYEGD GLNCVYIPKV MIEPSGPIHV
PKGNGTISKG DGGHSNWIPD VGSTRWPLKT PYIPPVITNR PTSKPTTRPA PRPTAELTPP
PFTELGTSPP ATSPDSPSTR LTPATPIATT SPRWITVDNR IHTDPQKPRG DVFIPRQPSN
DLFEIFEIER GVSADDEAKD DPGVLIHSCN FDHGLCGWIR EKDSDLHWEP VRDPTGGQYL
TVSGAKGPGG KAARLVLSLG HLMHSGDLCL SFRHKVTGLH SGALQVFVRK HSAHGAALWG
RNGGHGWRHT QITLQGADVK SVIFRGEKRR GHTGEIGLDD VSLRKGHCSE EREQLPN
//
