ID A0A2U3WEN6_ODORO Unreviewed; 976 AA.
AC A0A2U3WEN6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Protein transport protein Sec24C isoform X3 {ECO:0000313|RefSeq:XP_004407075.1};
GN Name=SEC24C {ECO:0000313|RefSeq:XP_004407075.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004407075.1};
RN [1] {ECO:0000313|RefSeq:XP_004407075.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Cytoplasmic vesicle, COPII-coated
CC vesicle membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004397}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
CC {ECO:0000256|ARBA:ARBA00008334}.
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DR RefSeq; XP_004407075.1; XM_004407018.2.
DR AlphaFoldDB; A0A2U3WEN6; -.
DR GeneID; 101365526; -.
DR CTD; 9632; -.
DR OrthoDB; 977017at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0030127; C:COPII vesicle coat; IEA:InterPro.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd01479; Sec24-like; 1.
DR Gene3D; 2.60.40.1670; beta-sandwich domain of Sec23/24; 1.
DR Gene3D; 1.20.120.730; Sec23/Sec24 helical domain; 1.
DR Gene3D; 3.40.20.10; Severin; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR036180; Gelsolin-like_dom_sf.
DR InterPro; IPR006900; Sec23/24_helical_dom.
DR InterPro; IPR036175; Sec23/24_helical_dom_sf.
DR InterPro; IPR006896; Sec23/24_trunk_dom.
DR InterPro; IPR012990; Sec23_24_beta_S.
DR InterPro; IPR041742; Sec24-like_trunk_dom.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR006895; Znf_Sec23_Sec24.
DR InterPro; IPR036174; Znf_Sec23_Sec24_sf.
DR PANTHER; PTHR13803:SF5; PROTEIN TRANSPORT PROTEIN SEC24C; 1.
DR PANTHER; PTHR13803; SEC24-RELATED PROTEIN; 1.
DR Pfam; PF00626; Gelsolin; 1.
DR Pfam; PF08033; Sec23_BS; 1.
DR Pfam; PF04815; Sec23_helical; 1.
DR Pfam; PF04811; Sec23_trunk; 1.
DR Pfam; PF04810; zf-Sec23_Sec24; 1.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF82754; C-terminal, gelsolin-like domain of Sec23/24; 1.
DR SUPFAM; SSF81811; Helical domain of Sec23/24; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR SUPFAM; SSF82919; Zn-finger domain of Sec23/24; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 304..342
FT /note="Zinc finger Sec23/Sec24-type"
FT /evidence="ECO:0000259|Pfam:PF04810"
FT DOMAIN 381..625
FT /note="Sec23/Sec24 trunk"
FT /evidence="ECO:0000259|Pfam:PF04811"
FT DOMAIN 630..713
FT /note="Sec23/Sec24 beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF08033"
FT DOMAIN 726..825
FT /note="Sec23/Sec24 helical"
FT /evidence="ECO:0000259|Pfam:PF04815"
FT DOMAIN 845..917
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT REGION 1..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..132
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..183
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 976 AA; 106615 MW; 7121F02F5FE67DE2 CRC64;
MQIGGAVAPA LPPVRLGYGP PTSLAPASGS YPNSGLYGSY PQGQAPPLSQ AQGHLGAQPP
QRSAPPQASG FTSPASGGPP MPSVTGPLLP GQGFGGPSVS QPNHVSSPPP QALPPGTQMT
GPPGPPPPMH SSQQPGYQLQ QNGSFGPARG PQPNYGSPYP GAPTFGSQPG PPQPLPPKRL
DPDAIPSPQL NELPPQQKTR HRIDPDAIPS PIQVIEDDRN NRGSEPFVTG VRGQVPPLVT
TNFLVKDQGN ASPRYIRCTS YNIPCTSDMA KQAQVPLAAV IKPLARLPPE EASPYVVDHG
ESGPLRCNRC KAYMCPFMQF VEGGRRFQCC FCSCINDVPP QYFQHLDHTG KRVDAYDRPE
LSLGSYEFLA TVDYCKNNKF PSPPAFIFMI DVSYNAIRSG LVRLLCEELK SLLDFLPREG
GAEESAIRVG FVTYNKVLHF YNVKSSLAQP QMMVVSDVAD MFVPLLDGFL VNVSESRAVI
TSLLDQIPEM FADTRETETV FAPVIQAGME ALKAAECAGK LFLFHTSLPI AEAPGKLKNR
DDRKLINTDK EKTLFQPQTG AYQTLAKECV AQGCSVDLFL FPNQYVDVAT LSVVPQLTGG
SVYKYACFQV ENDQERFLSD LRRDVQKVVG FDAVMRVRTS TGIRAVDFFG AFYMSNTTDV
ELAGLDGDKT VTVEFKHDDR LNEESGALLQ CALLYTSCAG QRRLRIHNLA LNCCTQLADL
YRNCETDTLI NYMAKFAYRG VLNSPVKTVR DTLITQCAQI LACYRKNCAS PSSAGQLILP
ECMKLLPVYL NCVLKSDVLQ PGAEVTTDDR AYVRQLVTSM DVAETNVFFY PRLLPLTKSP
IESATEPPAV RASEERLSNG DIYLLENGLN LFLWVGASVQ QGVVQSLFSV SSFSQITSGL
SVLPVLDNPL SKKVRGLIDS LRAQRSRYMK LIVVKQEDKL EMLFKHFLVE DKSLSGGASY
VDFLCHMHKE IRQLLS
//
