ID A0A2U3WJ25_ODORO Unreviewed; 440 AA.
AC A0A2U3WJ25;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Integral membrane protein GPR180 {ECO:0000313|RefSeq:XP_004408786.1};
GN Name=GPR180 {ECO:0000313|RefSeq:XP_004408786.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004408786.1};
RN [1] {ECO:0000313|RefSeq:XP_004408786.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_004408786.1; XM_004408729.2.
DR AlphaFoldDB; A0A2U3WJ25; -.
DR STRING; 9708.A0A2U3WJ25; -.
DR GeneID; 101380906; -.
DR KEGG; oro:101380906; -.
DR CTD; 160897; -.
DR InParanoid; A0A2U3WJ25; -.
DR OrthoDB; 5391031at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0019236; P:response to pheromone; IEA:InterPro.
DR InterPro; IPR047831; GPR180/TMEM145.
DR InterPro; IPR019336; GPR180/TMEM145_TM.
DR PANTHER; PTHR23252:SF29; INTEGRAL MEMBRANE PROTEIN GPR180; 1.
DR PANTHER; PTHR23252; INTIMAL THICKNESS RECEPTOR-RELATED; 1.
DR Pfam; PF10192; GpcrRhopsn4; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..440
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015676120"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 143..405
FT /note="GPR180/TMEM145 transmembrane"
FT /evidence="ECO:0000259|Pfam:PF10192"
SQ SEQUENCE 440 AA; 49198 MW; 7D9F4FEE0BB78A63 CRC64;
MGALRLLAVA LTCCWWPPGS QGKTLRGSFS SAAARDAEGQ SIGHFEFHGD HALLCVRINN
IAVAVGKEAK LYLFQAQEWL KLQDSSHGYS CGEKLSKAQL TMTMNQTEHN LTVSQVPYPQ
TWHVFYADKY TCKNDNENSQ AEEIPFEMML LNPDAEGNPF DHFSAGESGL HEFFFLLVLV
YFVLACIYAQ SLWQAIKKGG PMHVILKVLT AALLLQAGSA LANYIHFSSY SKDGIGIPFM
GSLAEFFDIA SQIQMLYLLL SLCMGWTIVR MKKSQSRPLQ WDSTPASTGI AVFIVITQSI
LLLWEQFEDT SPHSYHSHHN LAGILLIILR ICLALSLGCG LYQIITVERS TLKREFYITF
AKGCILWFLC HPGLACISVI FSDYQRDKVI TIGVILCQSV SMVILYRLFL SHSLYWEVSS
LSSVTLPLTI SSGHKSRPHF
//
