ID A0A2U3WLB6_ODORO Unreviewed; 1189 AA.
AC A0A2U3WLB6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Bromodomain-containing protein 1 isoform X1 {ECO:0000313|RefSeq:XP_004409729.1};
GN Name=BRD1 {ECO:0000313|RefSeq:XP_004409729.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004409729.1};
RN [1] {ECO:0000313|RefSeq:XP_004409729.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_004409729.1; XM_004409672.2.
DR AlphaFoldDB; A0A2U3WLB6; -.
DR STRING; 9708.A0A2U3WLB6; -.
DR GeneID; 101384825; -.
DR KEGG; oro:101384825; -.
DR CTD; 23774; -.
DR InParanoid; A0A2U3WLB6; -.
DR OrthoDB; 163389at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd05512; Bromo_brd1_like; 1.
DR CDD; cd15702; ePHD_BRPF2; 1.
DR CDD; cd15677; PHD_BRPF2; 1.
DR CDD; cd20157; PWWP_BRPF2; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR042004; BRPF2_ePHD.
DR InterPro; IPR042009; BRPF2_PHD.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF17; BROMODOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF10513; EPL1; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 2.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 214..264
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 268..389
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 579..649
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 1060..1143
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..912
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 926..998
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 515..558
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 801..815
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 933..947
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 982..998
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1189 AA; 133289 MW; 141144A76D6F5426 CRC64;
MRRKGRCHRG AAARHPSSPC STKHSPTRET LTYAQAQRMV EIEIEGRLHR ISIFDPLEII
LEDDLTAQEL SECNSNKENS ERPPVCLRTK RHKNNRVKKK HEAVPSAHGP LASASALPEP
KVRIVEYSPP SAPRRPPVYY KFIEKSAEEL DNEVEYDMDE EDYAWLEIVN EKRKGDCVSA
VSQSVFEFLM DRFEKESYCE NQKQGEQQSL IDEDAVCCIC MDGECQNSNV ILFCDMCNLA
VHQECYGVPY IPEGQWLCRH CLQSRARPAD CVLCPNKGGA FKKTDDDRWG HVVCALWIPE
VGFANTVFIE PIDGVRNIPP ARWKLTCYLC KQKGVGACIQ CHKANCYTAF HVTCAQKAGL
YMKMEPVKEL TGGATTFSVR KTAYCDVHTP PGCTRRPLNI YGDVEMKNGV CRKESSVKAV
RSTSKVRKKA KKAKKTLSEP CAALPPVCAP YIPPQRLNRI ANQVAIQRKK QFVERAHSYW
LLKRLSRNGA PLLRRLQSSL QSQRSSQQRE NDEEIQAAKE KLKYWQRLRH DLERARLLIE
LLRKREKLKR EQVKVEQMAL ELRLTPLTVL LRSVLDQLQE KDPARIFAQP VSLKEVPDYL
DHIKHPMDFA TMRKRLEAQG YRHLTEFEED FNLIVDNCMK YNAKDTVFYR AAVRLRDQGG
VVLRQARRQA DSIGFEEASG MHLPERPAAA PRRPFSWDDV DRLLNPANRA HMVLEEQLRE
LLDKLDLTCA MKSSGSRSKR AKLLRKEIAV LRNKLSQQHS QPPPAESGIG SFEEESAQLG
QETGEEGDKS PPKLEPSDAL PLPSNSETNS EPPTLKPVEL NPEQSKLFKR VTFDNESHST
CTQSALVIGH PPEPTLASSG DAPAAAASAV AEPASDVNRR TSVLFCKSKS VSPPKSAKNT
ETQPTSPQLG TKTFLSVVLP RLETLLQPRK RSRSTCGDSE VEEGSPGKRL DTGLTNGFGG
ARSEQELGGA PGRRPAPRRR CASESSISSS SSPLCDSSFS APKCGRGKPA LVRRHTLEDR
SELISCIENG NYAKAARIAA EVGQNSMWIS TDAAASVLEP LKVVWAKCSG YPSYPALIID
PKMPRVPGHH NGVTIPAPPL DVLKIGEHMQ TKADEKLFLV LFFDNKRSWQ WLPKSKMVPL
GMDETIDKLK MMEGRNSSIR KAVRVAFDRA MSHLSRVHGE PTSDLSDID
//
