ID   A0A2U3WLI5_ODORO        Unreviewed;       754 AA.
AC   A0A2U3WLI5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Amyloid beta A4 precursor protein-binding family A member 2 isoform X1 {ECO:0000313|RefSeq:XP_004409808.1};
GN   Name=APBA2 {ECO:0000313|RefSeq:XP_004409808.1};
OS   Odobenus rosmarus divergens (Pacific walrus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC   Odobenus.
OX   NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004409808.1};
RN   [1] {ECO:0000313|RefSeq:XP_004409808.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_004409808.1; XM_004409751.1.
DR   AlphaFoldDB; A0A2U3WLI5; -.
DR   STRING; 9708.A0A2U3WLI5; -.
DR   GeneID; 101363156; -.
DR   KEGG; oro:101363156; -.
DR   CTD; 321; -.
DR   InParanoid; A0A2U3WLI5; -.
DR   OrthoDB; 2881953at2759; -.
DR   Proteomes; UP000245340; Unplaced.
DR   CDD; cd00992; PDZ_signaling; 2.
DR   CDD; cd01208; PTB_X11; 1.
DR   Gene3D; 2.30.42.10; -; 2.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   PANTHER; PTHR12345:SF12; AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 2; 1.
DR   PANTHER; PTHR12345; SYNTENIN RELATED; 1.
DR   Pfam; PF00595; PDZ; 2.
DR   Pfam; PF00640; PID; 1.
DR   SMART; SM00228; PDZ; 2.
DR   SMART; SM00462; PTB; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 2.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50106; PDZ; 2.
DR   PROSITE; PS01179; PID; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          373..560
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   DOMAIN          573..658
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          664..740
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          1..94
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          136..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          186..228
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          242..351
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..40
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..94
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        143..167
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        275..290
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        299..317
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        326..351
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   754 AA;  82753 MW;  C0A5355EA65EB466 CRC64;
     MANRKRQSTA SSMLDHRARP GPMPHGQEPE SEDTELPLEE YVAKGLELAT LRPESPTPPD
     QGCHDHSPDG DSSSDYVNNT SEEEDYDEGL PEEEEGITYY IRYCPEDDSY LEGMDCNGEG
     YLAHGTRHLE TDECQEAVEE WTDSAGPRPH GHGDEGSPDF RDGHLPIPED EASVLEAQDQ
     EEGVHYCPGE EGYQDYYPTE ANGNTGNASP YRPRRGDGGL EDQEEDIDQI VAEIKMSLSM
     TSITSAGEAS PEHALVRGPE PGPGDSTEAC PPGEASHDPS RHEGRPKSLN LPPEAKHSGD
     PQRGFKTKSR TPEERPKWPQ EQVCNGLEQP RKQQRSDLNG PVDNNNTPET KKVASFPSFV
     AVPGPCEPED LIDGIIFAAN YLGSTQLLSE RNPSKNIRMM QAQEAVSRVK RMQKAAKIKK
     KANSEGDAQT LTEVDLFIST QRIKVLNADT QETMMDHALR TISYIADIGN IVVLMARRRM
     PRSASQDCIE TTPGAQEGKK QYKMICHVFE SEDAQLIAQS IGQAFSVAYQ EFLRANGINP
     EDLSQKEYSD IINTQEMYND DLIHFSNSEN CKELQLEKHK GEILGVVVVE SGWGSILPTV
     ILANMMNGGP AARSGKLSIG DQIMSINGTS LVGLPLATCQ GIIKGLKNQT QVKLNIVSCP
     PVTTVLIKRP DLKYQLGFSV QNGIICSLMR GGIAERGGVR VGHRIIEING QSVVATAHEK
     IVQALSNSVG EIHMKTMPAA MFRLLTGQET PLYI
//