ID A0A2U3WUA1_ODORO Unreviewed; 538 AA.
AC A0A2U3WUA1;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=NADPH oxidase 4 isoform X3 {ECO:0000313|RefSeq:XP_004412997.1};
GN Name=NOX4 {ECO:0000313|RefSeq:XP_004412997.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004412997.1};
RN [1] {ECO:0000313|RefSeq:XP_004412997.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_004412997.1; XM_004412940.2.
DR AlphaFoldDB; A0A2U3WUA1; -.
DR GeneID; 101364154; -.
DR CTD; 50507; -.
DR OrthoDB; 367877at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR PANTHER; PTHR11972:SF209; NADPH OXIDASE 4; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 304..412
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 538 AA; 62352 MW; 9F8E8EFDEDB0E39D CRC64;
MAVSWRNWLA NEGVKHLCLF IWLSLNVLLF WKAFLLYNQG PEYHYLHQML GLGLCLSRAS
ASVLNLNCSL ILLPMCRTLL AYLRGSQKVP SRKTRRLLDK SRTFHITCGV TICIFSGVHV
AAHLVNALNF SVNYSEDFAE LNAARYRDED PRKLLFTTVP GLTGVGMVLV LFLMITASTY
AIRVSNYDIF WYTHNLFFVF YMLLMLHVSG GLLKYQANLD THPPGCINPN GTRYQHIYLP
DHGSEHFHES FPGGPSKPDE LTQNRSVNIC VEEPRFQANF PQTWLWISGP LCLYCAERLY
RCIRSNKPVT IISVISHPSD VMEIRMIKEN FKARPGQYII LHCPSVSALE NHPFTLTMCP
TETKATFGVH LKIVGDWTER FRDLLLPLSN QDSEILPFIQ SRKYPKDDWK PYKLRRLYFI
WVCRDIQSFR WFADLLCVLH NKFWQENRPD YVNIQLYLSQ TDGIQKIIGE KYQALNSRLF
IGRPRWKLLF DEIAKCNRGK TVGVFCCGPN SISKTLHKLS NQNNPYGTRF EYNKESFS
//
