ID A0A2U3WV47_ODORO Unreviewed; 454 AA.
AC A0A2U3WV47;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Lamin-B1 isoform X2 {ECO:0000313|RefSeq:XP_004413328.1};
GN Name=LMNB1 {ECO:0000313|RefSeq:XP_004413328.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004413328.1};
RN [1] {ECO:0000313|RefSeq:XP_004413328.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Lamins are components of the nuclear lamina, a fibrous layer
CC on the nucleoplasmic side of the inner nuclear membrane, which is
CC thought to provide a framework for the nuclear envelope and may also
CC interact with chromatin. {ECO:0000256|ARBA:ARBA00037635}.
CC -!- SUBCELLULAR LOCATION: Nucleus lamina {ECO:0000256|ARBA:ARBA00024186}.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR RefSeq; XP_004413328.1; XM_004413271.2.
DR RefSeq; XP_012422418.1; XM_012566964.1.
DR RefSeq; XP_012422419.1; XM_012566965.1.
DR AlphaFoldDB; A0A2U3WV47; -.
DR GeneID; 101371343; -.
DR CTD; 4001; -.
DR OrthoDB; 72418at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005635; C:nuclear envelope; IEA:UniProt.
DR GO; GO:0005652; C:nuclear lamina; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.60.40.1260; Lamin Tail domain; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR001322; Lamin_tail_dom.
DR InterPro; IPR036415; Lamin_tail_dom_sf.
DR PANTHER; PTHR45721; LAMIN DM0-RELATED; 1.
DR PANTHER; PTHR45721:SF3; LAMIN-B1; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF00932; LTD; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
DR PROSITE; PS51841; LTD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023289};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Prenylation {ECO:0000256|ARBA:ARBA00023289};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340}.
SQ SEQUENCE 454 AA; 51661 MW; DAA4F18578573619 CRC64;
MKLREYEAAL NSKDAALATA LGDKKSLEGD LEDLKDQISQ LEASLAAAKK QLADETLLKV
DLENRCQSLT EDLEFRKNMY EEEINETRRK HETRLVEVDS GRQIEYEYKL AQALHEMREQ
HDAQVKLYKE ELEQTYHAKL ENARLSSEMN TSTVNSAREE LMESRMRIES LSSQLSNLQK
ESRACLERIQ ELEDLLAKER DNSRRMLSDK EREMAEIRDQ MQQQLNDYEQ LLDVKLALDM
EISAYRKLLE GEEERLKLSP SPSSRVTVSR ASSSRSVRTT RGKRKRVDVE ESEASSSVSI
SHSASATGNV CIEEIDVDGK FIRLKNTSEQ DQPMGGWEMI RKIGDTSVSY KYTSRYVLKA
GQTVTIWAAN AGVTASPPTD LIWKNQNSWG TGEDVKVILK NSQGEEVAQR STVFKTTIPE
EEEGEEDAPE VLAEEEIFHQ QGTTRASNRS CAIM
//
