ID A0A2U3WYT2_ODORO Unreviewed; 989 AA.
AC A0A2U3WYT2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Partitioning defective 3 homolog isoform X11 {ECO:0000313|RefSeq:XP_004414827.1};
GN Name=PARD3 {ECO:0000313|RefSeq:XP_004414827.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004414827.1};
RN [1] {ECO:0000313|RefSeq:XP_004414827.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endomembrane system
CC {ECO:0000256|ARBA:ARBA00004308}.
CC -!- SIMILARITY: Belongs to the PAR3 family.
CC {ECO:0000256|ARBA:ARBA00005358}.
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DR RefSeq; XP_004414827.1; XM_004414770.1.
DR AlphaFoldDB; A0A2U3WYT2; -.
DR GeneID; 101375042; -.
DR CTD; 56288; -.
DR OrthoDB; 5405986at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
DR CDD; cd00992; PDZ_signaling; 3.
DR Gene3D; 2.30.42.10; -; 3.
DR InterPro; IPR021922; Par3/HAL_N.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR16484:SF10; PARTITIONING DEFECTIVE 3 HOMOLOG; 1.
DR PANTHER; PTHR16484; PARTITIONING DEFECTIVE 3 RELATED; 1.
DR Pfam; PF12053; Par3_HAL_N_term; 1.
DR Pfam; PF00595; PDZ; 3.
DR SMART; SM00228; PDZ; 3.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR PROSITE; PS50106; PDZ; 3.
PE 3: Inferred from homology;
KW Cell junction {ECO:0000256|ARBA:ARBA00022427};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427}.
FT DOMAIN 271..347
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 462..547
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 578..653
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 80..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 154..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 815..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 887..989
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..202
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 914..931
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 932..971
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 989 AA; 108773 MW; 0E3D6788CC393CCA CRC64;
MKVTVCFGRT RVVVPCGDGH MKVFSLIQQA VTRYRKAIAK DPNYWIQVHR LEHGDGGILD
LDDTLCDVAD DKDRLVAVFD EQDPHHGGDG TSASSTGTQS PEIFGSELGT NSVSAFQPYQ
ATSEIEVTPS VLRANMPLHV RRSSDPALIG LSTSISDNNF SSEEPSRKNP TRWSTTAGFL
KQNTAGSPKT CDRKKDENYR SLPRDASNWS HQFQRDNARS SLSASHPMVD RWLEKQEQDE
DGTEEDNGRV EPVGHADTGL ENIPSFSLDD MVKLVRVPND GGPLGIHVVP FSARGGRTLG
LLVKRLEKGG KAEQENLFHE NDCIVRINDG DLRNRRFEQA QHMFRQAMRT PIIWFHVVPA
ANKEQYEQLS QSEKNNYYSS RFSPDSQYMD NRSVNSAGLP ALQRAPRLNH PPEQIDSHPR
LLPQSTHPSG KPPAAPAPAP QNVFSTNVSS GYNTKKIGKR LNIQLKKGTE GLGFSITSRD
VTIGGSAPIY VKNILPRGAA IQDGRLKAGD RLIEVNGVDL AGKSQEEVVS LLRSTKMEGT
VSLLVFRQED AFHPRELKAE DEDIVLTPDG TREFLTFEVP LNDSGSAGLG VSVKGNRSKE
NHADLGIFVK SIINGGAASK DGRLRVNDQL IAVNGESLLG KTNQDAMETL RRSMSTEGNK
RGMIQLIVAR RISKCNELKS PGSPSGPELP IETVLDDRER RISHSLYSGI EGLDESPTRN
AALSRIMGKY QLSPTVNMPQ DDTVIIEDDR LPVLPPHLSD QSSSSSHDDV GFVTTDAGTW
AKSAISDSAD CSLSPDVDPV LAFQREGFGR QIADETKLNT VDDQKAGSPS RDVGPSLGLK
KSSSLESLQT AVAEVTLNGD IPFHRPRPRI IRGRGCNESF RAAIDKSYDK PAVDDDDEGM
ETLEEDTEES SRSGRESVST ASDQPSHSLE RHMNGNQEKG DKMDRRKEKA GKEKKKDRDK
EKEKMKAKKG MLKGLGDMFS LAKLKPEKR
//
