ID   A0A2U3X096_ODORO        Unreviewed;       306 AA.
AC   A0A2U3X096;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Palmitoyl-protein thioesterase 1 {ECO:0000256|ARBA:ARBA00014212};
DE            EC=3.1.2.22 {ECO:0000256|ARBA:ARBA00012423};
DE   AltName: Full=Palmitoyl-protein hydrolase 1 {ECO:0000256|ARBA:ARBA00031934};
GN   Name=PPT1 {ECO:0000313|RefSeq:XP_004415419.1};
OS   Odobenus rosmarus divergens (Pacific walrus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC   Odobenus.
OX   NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004415419.1};
RN   [1] {ECO:0000313|RefSeq:XP_004415419.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + S-hexadecanoyl-L-cysteinyl-[protein] = H(+) +
CC         hexadecanoate + L-cysteinyl-[protein]; Xref=Rhea:RHEA:19233,
CC         Rhea:RHEA-COMP:10131, Rhea:RHEA-COMP:11032, ChEBI:CHEBI:7896,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29950,
CC         ChEBI:CHEBI:74151; EC=3.1.2.22;
CC         Evidence={ECO:0000256|ARBA:ARBA00000072};
CC   -!- SIMILARITY: Belongs to the palmitoyl-protein thioesterase family.
CC       {ECO:0000256|ARBA:ARBA00010758}.
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DR   RefSeq; XP_004415419.1; XM_004415362.2.
DR   AlphaFoldDB; A0A2U3X096; -.
DR   STRING; 9708.A0A2U3X096; -.
DR   GlyCosmos; A0A2U3X096; 3 sites, No reported glycans.
DR   GeneID; 101386758; -.
DR   KEGG; oro:101386758; -.
DR   CTD; 5538; -.
DR   InParanoid; A0A2U3X096; -.
DR   OrthoDB; 760135at2759; -.
DR   Proteomes; UP000245340; Unplaced.
DR   GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002472; Palm_thioest.
DR   PANTHER; PTHR11247:SF8; PALMITOYL-PROTEIN THIOESTERASE 1; 1.
DR   PANTHER; PTHR11247; PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1; 1.
DR   Pfam; PF02089; Palm_thioest; 1.
DR   PRINTS; PR00414; PPTHIESTRASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..306
FT                   /note="Palmitoyl-protein thioesterase 1"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015657481"
SQ   SEQUENCE   306 AA;  34039 MW;  2D9636AC0EA4E175 CRC64;
     MASPGCLWLL AAALLPGSCA ARALGRLDPA APLPLVIWHG MGDSCCNPLS MGAIKKMVEK
     KIPGIYVLSL EIGKTLMEDV ENSFFLNVNS QVTTVCQILA KDPKLQQGYN AMGFSQGGQF
     LRAVAQRCPS PPMINLISVG GQHQGVYGLP RCPGESSHIC DLIRKTLNAG AYNKAIQERL
     VQAEYWHDPI KEDMYRNHSI FLADINQERG VNESYKKNLM ALKKFVMVKF LNDSIVDPVD
     SEWFGFYRSG QAKETIPLQE TTLYTQDRLG LKEMDSAGQL VFLAVEGDHL QLSQEWFYAH
     IIPFLE
//