ID   A0A2U3X0W4_ODORO        Unreviewed;      1080 AA.
AC   A0A2U3X0W4;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=DNA helicase B {ECO:0000313|RefSeq:XP_004415672.1};
GN   Name=HELB {ECO:0000313|RefSeq:XP_004415672.1};
OS   Odobenus rosmarus divergens (Pacific walrus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC   Odobenus.
OX   NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004415672.1};
RN   [1] {ECO:0000313|RefSeq:XP_004415672.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_004415672.1; XM_004415615.1.
DR   AlphaFoldDB; A0A2U3X0W4; -.
DR   GeneID; 101383648; -.
DR   KEGG; oro:101383648; -.
DR   CTD; 92797; -.
DR   InParanoid; A0A2U3X0W4; -.
DR   OrthoDB; 5305157at2759; -.
DR   Proteomes; UP000245340; Unplaced.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   CDD; cd17933; DEXSc_RecD-like; 1.
DR   CDD; cd18809; SF1_C_RecD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR006594; LisH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   PANTHER; PTHR43788:SF21; DNA HELICASE B; 1.
DR   PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF13604; AAA_30; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS50896; LISH; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|RefSeq:XP_004415672.1};
KW   Hydrolase {ECO:0000313|RefSeq:XP_004415672.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245340}.
FT   DOMAIN          869..915
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13538"
FT   REGION          167..190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          392..413
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          781..804
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          959..1039
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..187
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        959..989
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1011..1026
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1080 AA;  121681 MW;  6D40494FE473BC97 CRC64;
     MAFLSQHLRE LQGPLLPPKD LVEEDDDCLK EDVAEDEDLE FVDAEELCSG GVKAGTLPGR
     LRVVISDENT QEQCDVFGRF PVTGPWWRVK VQVKPMGSRS YQVQGFPSYF LQSDMSPPNQ
     THICSLFLKD CNFSSDYINK FLAWVSAVSS FKNLNFENLR ETLRTFQKET GRNGQKQSTQ
     NEQEESLPEN EMCLPLENTT PFKSVMTALQ FPKVMEFLPV LLPRHFKWLL SSGSKEVLED
     LEEMLGTHPW KLGFSKITYT ELKLLQCEAS WASFCQCKSL LQLMSDLEKN ALIIYSKLRH
     ICRDQGHTCI EEADLTSKLS DHMSFQDAWQ SLKFLKDIGV VTYEKGCVFL YDLYQAERGI
     ASSICDLMTR PPWHLHVDVK RVLALIHTTK PENSESDKTL NESQPDETGL ENPVAVLDPQ
     DSGDHVWSNG ESEVNVEISE AHLDQDQVAA LEMVCSNAVT VISGKGGCGK TTIVSHLFKH
     MEQLEEREVK KACEDFEQDQ DVSEEWITFT EQSLLKADKA IEVLLTAPTG KAAALLREKT
     GFNAYTLCQV NYSFYLWEKK SPAKNRPWKF SSVRVLVVDE GSLVSVRIFK SVLKLLCEHS
     KLSKLIILGD IRQLPSIEPG NLLIDLFETL KSRNCAIELK KNHRAESELI VNNATRISRR
     QFPIFDAELN ISDKLTLPAS IQDKTFIFIR LPEEDASSQL SENDPPSYLY SAVRTLLKEN
     DLQDAQTSQF IAFRRQDCDV INACCCKHYT GHLIKDHRNR LQFGVGDKIC CTRNAYLSEL
     LPGRTSPSQE SNEREASGED FNGTPHGFAK NKHDFESDIR LCNGEIFFIT KDVTDVTFGK
     RRSLTINNAA GLEITVDFEK LMKYCHIKHA WARTIHTFQG SEEKTVVYVV GKAGRQHWQH
     VYTAVTRGRC RVYVIAEESH LRSAIMRNSV LRKTRLKHFL QNKLSTSCVS PADLASLSRS
     SGESRGLSTQ PSASSVPPVT TTNVTAGVPG SGASAADDRT FAFPEGWKLS SSDEVDPEED
     PSELRGSKRA YGLSGAESPS KIRMVGVEEA SPQVSSRLQN LRLNRLTPRQ LFIPTNNQET
//