ID   A0A2U3X2L2_ODORO        Unreviewed;       941 AA.
AC   A0A2U3X2L2;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Superkiller viralicidic activity 2-like 2 isoform X2 {ECO:0000313|RefSeq:XP_004416372.1};
GN   Name=SKIV2L2 {ECO:0000313|RefSeq:XP_004416372.1};
OS   Odobenus rosmarus divergens (Pacific walrus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC   Odobenus.
OX   NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004416372.1};
RN   [1] {ECO:0000313|RefSeq:XP_004416372.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_004416372.1; XM_004416315.1.
DR   AlphaFoldDB; A0A2U3X2L2; -.
DR   GeneID; 101370395; -.
DR   CTD; 23517; -.
DR   OrthoDB; 1352at2759; -.
DR   Proteomes; UP000245340; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR   CDD; cd18024; DEXHc_Mtr4-like; 1.
DR   CDD; cd13154; KOW_Mtr4; 1.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 2.
DR   Gene3D; 2.40.30.300; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR048392; MTR4-like_stalk.
DR   InterPro; IPR025696; MTR4_beta-barrel.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016438; SKI2-like.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF21408; MTR4-like_stalk; 1.
DR   Pfam; PF13234; MTR4_beta-barrel; 1.
DR   PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245340}.
FT   DOMAIN          47..203
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          304..476
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   941 AA;  106586 MW;  7C568FF44DE9A810 CRC64;
     MEGAAGVCGK GRVALPADED YLPLKPRVGK AAKEYPFILD AFQREAIQCV DNNQSVLVSA
     HTSAGKTVCA EYAIALALRE KQRVIFTSPI KALSNQKYRE MYEEFQDVGL MTGDVTINPT
     ASCLVMTTEI LRSMLYRGSE VMREVAWVIF DEIHYMRDSE RGVVWEETII LLPDNVHYVF
     LSATIPNARQ FAEWICHLHK QPCHVIYTDY RPTPLQHYIF PAGGDGLHLV VDENGDFRED
     NFNTAMQVLR DAGDLAKGDQ KGRKGGTKGP SNVFKIVKMI MERNFQPVII FSFSKKDCEA
     YALQMTKLDF NTDEEKKMVE EVFSNAIDCL SDEDKKLPQV EHVLPLLKRG IGIHHGGLLP
     ILKETIEILF SEGLIKALFA TETFAMGINM PARTVLFTNA RKFDGKDFRW ISSGEYIQMS
     GRAGRRGMDD RGIVILMVDE KMSPTIGKQL LKGSADPLNS AFHLTYNMVL NLLRVEEINP
     EYMLEKSFYQ FQHYRAIPGV VEKVKNSEEQ YNKIVIPNEE SVIIYYKIRQ QLAKLGKEIE
     EYIHKPKYCL PFLQPGRLVK VKNEGDDFGW GVVVNFSKKS NVKPNSGELD PLYVVEVLLR
     CSKESLKNSA TEAAKPAKPD EKGEMQVVPV LVHLLSAISS VRLYIPKDLR PVDNRQSVLK
     SIQEVQKRFP DGVPLLDPID DMGIQDQGLK KVIQKVEAFE HRMYSHPLHN DPNLETVYTL
     CEKKAQIAID IKSAKRELKK ARTVLQMDEL KCRKRVLRRL GFATSSDVIE MKGRVACEIS
     SADELLLTEM MFNGLFNDLS AEQATALLSC FVFQENSSEM PKLTEQLAGP LRQMQECAKR
     IAKVSAEAKL EIDEETYLSS FKPHLMDVVY TWATGATFAH ICKMTDVFEG SIIRCMRRLE
     ELLRQMCQAA KAIGNTELEN KFAEGITKIK RDIVFAASLY L
//