ID   A0A2U3X6A5_LEPWE        Unreviewed;       291 AA.
AC   A0A2U3X6A5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=PTB domain-containing engulfment adapter protein 1 isoform X6 {ECO:0000313|RefSeq:XP_006727014.1};
GN   Name=GULP1 {ECO:0000313|RefSeq:XP_006727014.1};
OS   Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC   Leptonychotes.
OX   NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006727014.1};
RN   [1] {ECO:0000313|RefSeq:XP_006727014.1}
RP   IDENTIFICATION.
RC   TISSUE=Liver {ECO:0000313|RefSeq:XP_006727014.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_006727014.1; XM_006726951.2.
DR   AlphaFoldDB; A0A2U3X6A5; -.
DR   STRING; 9713.A0A2U3X6A5; -.
DR   GeneID; 102725844; -.
DR   KEGG; lww:102725844; -.
DR   CTD; 51454; -.
DR   OrthoDB; 2878524at2759; -.
DR   Proteomes; UP000245341; Unplaced.
DR   CDD; cd01273; PTB_CED-6; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   PANTHER; PTHR11232; PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER; 1.
DR   PANTHER; PTHR11232:SF78; PTB DOMAIN-CONTAINING ENGULFMENT ADAPTER PROTEIN 1; 1.
DR   Pfam; PF00640; PID; 1.
DR   SMART; SM00462; PTB; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS01179; PID; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT   DOMAIN          27..155
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   REGION          225..291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          159..200
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        275..291
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   291 AA;  33233 MW;  6F2EF46C2EACB480 CRC64;
     MNRAFSRKKD KTWMHTPEAL SKHYIPYNAK FLGSTEVEQP KGTEVVRDAV RKLKFARHIK
     KSEGQKIPKV ELQISIYGVK ILEPKTKEVQ HNCQLHRISF CADDKTDKRI FTFICKDSES
     NKHLCYVFDS EKCAEEITLT IGQAFDLAYR KFLESGGKDV ETRKQIAGLQ KRIQDLETEN
     MELKNKVQDL ESQLRITQVS TSPAGSVTPK SPSTDIFDMI PFSPISHPAS MPARNGTQPP
     PIPSRSTEIK RDLFGAEPFD PFNCGAGDFP PDIQSKLDEM QRQRWRGSKW D
//