ID   A0A2U3X878_LEPWE        Unreviewed;       421 AA.
AC   A0A2U3X878;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=LOW QUALITY PROTEIN: bile acid-CoA:amino acid N-acyltransferase {ECO:0000313|RefSeq:XP_006727689.1};
GN   Name=LOC102729479 {ECO:0000313|RefSeq:XP_006727689.1};
OS   Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC   Leptonychotes.
OX   NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006727689.1};
RN   [1] {ECO:0000313|RefSeq:XP_006727689.1}
RP   IDENTIFICATION.
RC   TISSUE=Liver {ECO:0000313|RefSeq:XP_006727689.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC       {ECO:0000256|ARBA:ARBA00006538}.
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DR   RefSeq; XP_006727689.1; XM_006727626.1.
DR   STRING; 9713.A0A2U3X878; -.
DR   GeneID; 102729479; -.
DR   KEGG; lww:102729479; -.
DR   OrthoDB; 5356064at2759; -.
DR   Proteomes; UP000245341; Unplaced.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR   InterPro; IPR014940; BAAT_C.
DR   InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR   InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR   PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR   PANTHER; PTHR10824:SF18; BILE ACID-COA:AMINO ACID N-ACYLTRANSFERASE; 1.
DR   Pfam; PF08840; BAAT_C; 1.
DR   Pfam; PF04775; Bile_Hydr_Trans; 1.
DR   PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT   DOMAIN          14..144
FT                   /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT                   acid N-acetyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF04775"
FT   DOMAIN          207..414
FT                   /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08840"
FT   ACT_SITE        235
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        329
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        363
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ   SEQUENCE   421 AA;  46600 MW;  1C71D250748FA08F CRC64;
     MIHLTATPAS ALIDEPVHIR ATGLSPFQIM ILQASLKDEK GNRFHSQAYY KANEVGEVDL
     EHAPSLGGDY IGVHPMGLFW SLKPEKFLTK LLKRDVMNSP FLVQIKLYDS NLLLTDIATT
     APKVSLTLER WYIALGVKRI QVREGHLRGA LFLPPGEGCF PGVIDLFGRI GGLIEFWASL
     LASHGFVALA LDYFNYEDLP SQPEKTXLEY FEEAVNFLLR HPKVLGPGIG IVSISKGAEI
     GLSMATHLKQ VKATVLINGP NFAFSIPQVY SGQISQPLPF SPQLLSINAL GLAEFQHSFE
     EARSEASETS LLPIEKAPGH FLFIVGEDDK NINSKAXAKQ ATEQLRRYGK NSWTLLSYPG
     AGHLLEPPYS PLCCASKISN LHLFMHWGGE VTPHVAAQEH SWKEIQKFLR KHLVPVVTSQ
     L
//