ID   A0A2U3XHA3_LEPWE        Unreviewed;       318 AA.
AC   A0A2U3XHA3;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Methyltransferase-like protein 9 isoform X1 {ECO:0000313|RefSeq:XP_006730865.1};
GN   Name=METTL9 {ECO:0000313|RefSeq:XP_006730865.1};
OS   Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC   Leptonychotes.
OX   NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006730865.1};
RN   [1] {ECO:0000313|RefSeq:XP_006730865.1}
RP   IDENTIFICATION.
RC   TISSUE=Liver {ECO:0000313|RefSeq:XP_006730865.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_006730865.1; XM_006730802.1.
DR   AlphaFoldDB; A0A2U3XHA3; -.
DR   STRING; 9713.A0A2U3XHA3; -.
DR   GeneID; 102734041; -.
DR   KEGG; lww:102734041; -.
DR   CTD; 51108; -.
DR   OrthoDB; 8628at2759; -.
DR   Proteomes; UP000245341; Unplaced.
DR   GO; GO:0106370; F:protein-L-histidine N-pros-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR007884; METL9.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR12890; DREV PROTEIN; 1.
DR   PANTHER; PTHR12890:SF0; PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE; 1.
DR   Pfam; PF05219; DREV; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW   Methyltransferase {ECO:0000313|RefSeq:XP_006730865.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245341};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000313|RefSeq:XP_006730865.1}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..318
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015626235"
SQ   SEQUENCE   318 AA;  36598 MW;  0E4BAAA5DFB0157F CRC64;
     MRLFVGWLCL SLASVWLARR MWTLRSPLTR SLYVNMTSGP GGPAAAAGGR KENHQWYVCN
     REKLCESLQA VFVQSYLDQG TQIFLNNSIE KSGWLFIQLY HSFVSSVFSL FMSRTSINGL
     LGRGSMFVFS PDQFQRLLKI NPDWKTHRLL DLGAGDGEVT KIMSPHFEEI YATELSETMI
     WQLQKKKYRV LGINEWQNTG FQYDVISCLN LLDRCDQPLT LLKDIRSVLE PTRGRVILAL
     VLPFHPYVEN VGGKWEKPSE ILEIKGQNWE EQVNSLPEVF RKAGFVIEAF TRLPYLCEGD
     MYNDYYVLDD AVFVLKPV
//