ID A0A2U3XPK1_LEPWE Unreviewed; 462 AA.
AC A0A2U3XPK1;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Nuclear factor interleukin-3-regulated protein {ECO:0000313|RefSeq:XP_006733404.1};
GN Name=NFIL3 {ECO:0000313|RefSeq:XP_006733404.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006733404.1};
RN [1] {ECO:0000313|RefSeq:XP_006733404.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006733404.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the bZIP family. NFIL3 subfamily.
CC {ECO:0000256|ARBA:ARBA00006079}.
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DR RefSeq; XP_006733404.1; XM_006733341.2.
DR AlphaFoldDB; A0A2U3XPK1; -.
DR STRING; 9713.A0A2U3XPK1; -.
DR GeneID; 102734653; -.
DR KEGG; lww:102734653; -.
DR CTD; 4783; -.
DR OrthoDB; 4467729at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0007623; P:circadian rhythm; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd14694; bZIP_NFIL3; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR047229; NFIL3-like.
DR InterPro; IPR047106; NFIL3-like_bZIP.
DR InterPro; IPR010533; Vert_IL3-reg_TF.
DR PANTHER; PTHR15284; NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN; 1.
DR PANTHER; PTHR15284:SF1; NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN; 1.
DR Pfam; PF07716; bZIP_2; 1.
DR Pfam; PF06529; Vert_IL3-reg_TF; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 3: Inferred from homology;
KW Biological rhythms {ECO:0000256|ARBA:ARBA00023108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000245341};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 73..123
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 254..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..294
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 462 AA; 50762 MW; 3574C0C8C94242C2 CRC64;
MQLRKMQTIK KEQASLDAGS GVDKMMVLNS ALTEVSEDLT GGEELLLNEG SVGKSKSSAC
RRKREFIPDE KKDAMYWEKR RKNNEAAKRS REKRRLNDLV LENKLIALGE ENATLKAELL
SLKLKFGLIS STAYAQEIQK LSHSTAVYFQ DYQASKSSTG PFVDEHEPSM VTSGCISVIK
HSPQASLSDV PEVSSLERSQ DGAVQGGCGS PESKFQAIKQ EPVELESYAR EPGDERGAYR
ASVYQNLMGT AFPSYSHSPP LLQVTRSSSN SPRTSETDDG TVGKSSDGED EQQVPKGPIH
SPVELQRGHA TTVKVPEVNS SALPHKLRIK AKAMQIKVEA FDHEFDAAPK PASPMDGTPK
RHFELEKHTA PSMVHSALTP FSVQVTNIQD WSLKSEHWHP KELNGKTQNS FKTGVVEMQD
SGYKVSDPEN LFLKQGIANL SAEVVSLKRL IATHQISASD SG
//
