ID A0A2U3XQS9_LEPWE Unreviewed; 447 AA.
AC A0A2U3XQS9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Zinc finger protein 3 isoform X1 {ECO:0000313|RefSeq:XP_030884489.1, ECO:0000313|RefSeq:XP_030884490.1};
DE SubName: Full=Zinc finger protein 3 isoform X2 {ECO:0000313|RefSeq:XP_006733816.1};
GN Name=ZNF3 {ECO:0000313|RefSeq:XP_006733816.1,
GN ECO:0000313|RefSeq:XP_030884489.1, ECO:0000313|RefSeq:XP_030884490.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006733816.1};
RN [1] {ECO:0000313|RefSeq:XP_006733816.1, ECO:0000313|RefSeq:XP_030884489.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006733816.1,
RC ECO:0000313|RefSeq:XP_030884489.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_006733816.1; XM_006733753.2.
DR RefSeq; XP_030884489.1; XM_031028629.1.
DR RefSeq; XP_030884490.1; XM_031028630.1.
DR GeneID; 102746471; -.
DR KEGG; lww:102746471; -.
DR CTD; 7551; -.
DR OrthoDB; 4624799at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR19818:SF168; GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED; 1.
DR PANTHER; PTHR19818; ZINC FINGER PROTEIN ZIC AND GLI; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 8.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000245341};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 52..124
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 201..228
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 229..256
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 257..284
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 285..312
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 313..340
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 341..368
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 369..396
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 397..424
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 447 AA; 50719 MW; C212B846B983A467 CRC64;
METQADCVSQ EPQALLESAL PSSTVPAFSD KDSLGDEMLA AALLKAKSQE LVTFEDVAVY
FIRKEWKRLE PAQRDLYRDV MLENYGNVFS LDGETRTEHD QEISEDTGSH GVLLGRFQKD
ISQGLKFEEA YEQEVSLKRQ LGNSSGERLN RKIQDFGQVT DEEKLTPVGE RSEKYSDFGN
SFTVSSNLIS HQRLPVGDRP HKCDECSKSF NRTSDLIQHQ RIHTGEKPYE CSECGKAFSQ
SSHLIQHQRI HTGEKPYECN DCGKTFSCSS ALILHRRIHT GEKPYECSEC GKTFSWSSTL
THHQRIHTGE KPYACNECGK AFSRSSTLIH HQRIHTGEKP YECNECGKAF SQSSHLYQHQ
RIHTGEKPYE CMECGGKFTY SSGLIQHQRI HTGENPYECS ECGKAFRYSS ALVRHQRIHT
GEKPLNVMGM SKSSLRVTAE LNIREST
//
