ID A0A2U3XRZ8_LEPWE Unreviewed; 542 AA.
AC A0A2U3XRZ8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Myotubularin-related protein 9-like isoform X1 {ECO:0000313|RefSeq:XP_006734224.1};
GN Name=LOC102728317 {ECO:0000313|RefSeq:XP_006734224.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006734224.1};
RN [1] {ECO:0000313|RefSeq:XP_006734224.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006734224.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
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DR RefSeq; XP_006734224.1; XM_006734161.2.
DR AlphaFoldDB; A0A2U3XRZ8; -.
DR STRING; 9713.A0A2U3XRZ8; -.
DR GeneID; 102728317; -.
DR KEGG; lww:102728317; -.
DR OrthoDB; 5474662at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR CDD; cd14536; PTP-MTMR9; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR InterPro; IPR030564; Myotubularin_fam.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR PANTHER; PTHR10807:SF52; MYOTUBULARIN PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR Pfam; PF06602; Myotub-related; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT DOMAIN 124..502
FT /note="Myotubularin phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51339"
SQ SEQUENCE 542 AA; 60673 MW; 81D4D95739E229B6 CRC64;
MEFSELIRTG RAQAKLLRGP EAPPLRGTLC VTGHHLLLSP GPQATSDLWL LLLRRVDSIE
KRVSGDSGTI TLRCKDLRVL QLDIEGVEAT LDIARSIEAL SSLESVITSF PFFYRPKGLR
LGDAWHFHPP ERYYKRVARE TNAWRLSEVN GDFSLCPSYP RAVIVPRAVD DDALARCARF
RQGGRFPVLS YHHAPSGTVL LRSSQPLTGP QKRRCAEDEE LLRAVLAGAR PGARGFVLDT
RSAQAAKQAR VTGGGTEAKA AYPGWKRLHR PLERGWPLQE SFVRLVEACG DLEQSMDRWL
SHLEACHWLA HVKEALSTAC LAAQGVGREG ACVLVHGAEG MDSTLLVTSL AQLILDPSSR
TIAGFQELVE REWIQAGHPF QLRCAHSAFS HARPKHEAPT FLLFLDCVWQ LGRQFPLSLE
FGEGLLLALF EHAYASPFGT FLCSSEKERC LCEVRTRTHS LWSGLNQPKE QRKLRNPLYV
PNPLAIWPSV ELQTLRLWQG LFLRWIRPPE SSEVAWEKVW QIVTDKKTEG CEPTVSASEP
QL
//
