ID A0A2U3XZH3_LEPWE Unreviewed; 226 AA.
AC A0A2U3XZH3;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Histone H1.5 {ECO:0000313|RefSeq:XP_006736836.1};
GN Name=H1-5 {ECO:0000313|RefSeq:XP_006736836.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006736836.1};
RN [1] {ECO:0000313|RefSeq:XP_006736836.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006736836.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003894}.
CC -!- SIMILARITY: Belongs to the histone H1/H5 family.
CC {ECO:0000256|RuleBase:RU003894}.
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DR RefSeq; XP_006736836.1; XM_006736773.2.
DR AlphaFoldDB; A0A2U3XZH3; -.
DR STRING; 9713.A0A2U3XZH3; -.
DR GeneID; 102738888; -.
DR KEGG; lww:102738888; -.
DR CTD; 3009; -.
DR OrthoDB; 5362469at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR CDD; cd00073; H15; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005819; H1/H5.
DR InterPro; IPR005818; Histone_H1/H5_H15.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00538; Linker_histone; 1.
DR PRINTS; PR00624; HISTONEH5.
DR SMART; SM00526; H15; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51504; H15; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|RuleBase:RU003894};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003894};
KW Nucleus {ECO:0000256|RuleBase:RU003894};
KW Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT DOMAIN 39..112
FT /note="H15"
FT /evidence="ECO:0000259|PROSITE:PS51504"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 94..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..226
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 226 AA; 22531 MW; 93E9F902A8B78FFF CRC64;
MSETAPADTA APAPVEKSPA KKKATKKAAG GGAAKRKASG PPVSELIIKA VAASKERSGV
SLAALKKALA AAGYDVEKNN SRIKLGLKSL VSKGTLVQTK GTGASGSFKL NKKAASGEAK
PKAKKAGAAK AKKPSGATPK KPKKAAGAKK AVKKTPKKAK KPAAAGVKKV AKSPKKAKAA
AKPKKAAKSP AKPKAVKPKA AKPKAAKPKA AKPKAAKAKK AAPKKK
//
