ID A0A2U3Y5F9_LEPWE Unreviewed; 242 AA.
AC A0A2U3Y5F9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Cytochrome b5 domain-containing protein 1 {ECO:0000256|ARBA:ARBA00040649};
GN Name=LOC102750744 {ECO:0000313|RefSeq:XP_006738945.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006738945.1};
RN [1] {ECO:0000313|RefSeq:XP_006738945.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006738945.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}.
CC -!- SIMILARITY: Belongs to the cytochrome b5 family.
CC {ECO:0000256|ARBA:ARBA00038168}.
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DR RefSeq; XP_006738945.1; XM_006738882.2.
DR AlphaFoldDB; A0A2U3Y5F9; -.
DR STRING; 9713.A0A2U3Y5F9; -.
DR GeneID; 102750744; -.
DR KEGG; lww:102750744; -.
DR OrthoDB; 5470710at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR PANTHER; PTHR21281:SF0; CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR21281; UNCHARACTERIZED; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT DOMAIN 31..146
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
SQ SEQUENCE 242 AA; 28146 MW; 861D409F30148C8C CRC64;
MKQPETQVAD GARAVPRRGL VGGPDFEFFR RRYFTPAEVA QHNAPEDLWV SYLGSVYDLT
PLARKYKGDL LLKPIVEVAG QDISHWFDPK TRDIRKHVDP LTGTLRYRTP RGRFLHVPPQ
LPRSDWANDF GKPWWQGVRY EVGRLSAKTR NIRIINTLTS QEHALEVGAQ ESMWEILHRC
LPFNAHAASY TWKYEGKKLN MDYTLEENGI RDEDEEFDYL NMDGTLYTPA ILLYFDDDLT
EL
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