ID A0A2U3YBW8_LEPWE Unreviewed; 253 AA.
AC A0A2U3YBW8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Bridging integrator 3 isoform X1 {ECO:0000313|RefSeq:XP_006741192.1};
GN Name=BIN3 {ECO:0000313|RefSeq:XP_006741192.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006741192.1};
RN [1] {ECO:0000313|RefSeq:XP_006741192.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006741192.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR RefSeq; XP_006741192.1; XM_006741129.2.
DR AlphaFoldDB; A0A2U3YBW8; -.
DR STRING; 9713.A0A2U3YBW8; -.
DR GeneID; 102750177; -.
DR KEGG; lww:102750177; -.
DR CTD; 55909; -.
DR OrthoDB; 3075274at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0051666; P:actin cortical patch localization; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd07590; BAR_Bin3; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR046982; BIN3/RVS161-like.
DR InterPro; IPR037428; Bin3_BAR.
DR PANTHER; PTHR47174; BRIDGING INTEGRATOR 3; 1.
DR PANTHER; PTHR47174:SF3; BRIDGING INTEGRATOR 3; 1.
DR Pfam; PF03114; BAR; 1.
DR SMART; SM00721; BAR; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51021; BAR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT DOMAIN 9..232
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT REGION 221..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 24..51
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 121..148
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 253 AA; 29699 MW; CF3DAB1E14716B6C CRC64;
MSWIPFKIGQ PKKQIVPKTV ERDFEREYGK LQQLEEQTRR LQKDMKKSTD ADLAMSKSAV
KISLDLLSNP LCEQDQDFLN MVTALDTAMK RMDAFNQEKV NQIQKTVIEP LKKFGSVFPS
LNMAVKRREQ ALQDYRRLQA KVEKYEEKEK TGPVLAKLHQ AREELRPVRD DFEAKNKQLL
DEMPRFYHSR LDYFQPSFEA LIRAQVGYYS EMQKIFGDLT QQLDQPGHPD EQRERENEAR
LSELRALSIV ADD
//
