ID A0A2U3YD76_LEPWE Unreviewed; 524 AA.
AC A0A2U3YD76;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Tigger transposable element-derived protein 6 {ECO:0000313|RefSeq:XP_006741689.1};
GN Name=TIGD6 {ECO:0000313|RefSeq:XP_006741689.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006741689.1};
RN [1] {ECO:0000313|RefSeq:XP_006741689.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006741689.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00320}.
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DR RefSeq; XP_006741689.1; XM_006741626.2.
DR AlphaFoldDB; A0A2U3YD76; -.
DR STRING; 9713.A0A2U3YD76; -.
DR GeneID; 102738601; -.
DR KEGG; lww:102738601; -.
DR CTD; 81789; -.
DR OrthoDB; 2382272at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR007889; HTH_Psq.
DR PANTHER; PTHR19303:SF52; TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 6; 1.
DR PANTHER; PTHR19303; TRANSPOSON; 1.
DR Pfam; PF04218; CENP-B_N; 1.
DR Pfam; PF03184; DDE_1; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50960; HTH_PSQ; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT DOMAIN 3..54
FT /note="HTH psq-type"
FT /evidence="ECO:0000259|PROSITE:PS50960"
FT DOMAIN 66..137
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DNA_BIND 30..50
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00320"
SQ SEQUENCE 524 AA; 58946 MW; D79B1EB98C080980 CRC64;
MANKGNKKRR QFSLEEKMKV VEAVDSGKRK GDVAKEFGIT PSTLSTFLKD RAKFEEKVRE
ASVGPQRKRM RNALYDDIDK AVFAWFQEIH AKNILVTGSV IRKKALNLAN MLGYDNFQAS
VGWLNRFRDR HGIALKAVCR EDSDRLMNGL GIDKVNEWHA GEIIKLIADY SPDDIFNADE
TGVFFQLLPQ HTLAAKGDHC RGGKKAKQRL TALFCCNASG TEKMRPLIVG RSANPHCLKN
VHSLPCDYRA NQGAWMTQEL FNEWLMQVDA RMKRAERRIL LLIDNCSAHN MLPRLERIQV
GYLPSNCTAV LQPLNLGIIR TMKVLYRSHL LKQILLKLHS SEDQEKVDIR QAIDMIAAAW
WSVKQSTVVR CWQKAGIIPL ELTDSDTEVA ASEPEAASEK LWHSVALATC VPNEINFQDF
VTADDDLIIS QEQIDTEVIQ GMEAGENTDE AGSEEEGEAS LPQQPKITIT EAISSVQKLR
QFLSTCVGVP DAVFGQLNGI DEYLMRKVTQ TLVDSKITDF LQTK
//
