ID A0A2U3YH83_LEPWE Unreviewed; 548 AA.
AC A0A2U3YH83;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Tigger transposable element-derived protein 7 {ECO:0000313|RefSeq:XP_006743079.1};
GN Name=TIGD7 {ECO:0000313|RefSeq:XP_006743079.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006743079.1};
RN [1] {ECO:0000313|RefSeq:XP_006743079.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006743079.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00320}.
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DR RefSeq; XP_006743079.1; XM_006743016.2.
DR RefSeq; XP_006743080.1; XM_006743017.1.
DR AlphaFoldDB; A0A2U3YH83; -.
DR STRING; 9713.A0A2U3YH83; -.
DR GeneID; 102740608; -.
DR KEGG; lww:102740608; -.
DR CTD; 91151; -.
DR OrthoDB; 2967227at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR007889; HTH_Psq.
DR PANTHER; PTHR19303:SF17; TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 7; 1.
DR PANTHER; PTHR19303; TRANSPOSON; 1.
DR Pfam; PF04218; CENP-B_N; 1.
DR Pfam; PF03184; DDE_1; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50960; HTH_PSQ; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT DOMAIN 1..52
FT /note="HTH psq-type"
FT /evidence="ECO:0000259|PROSITE:PS50960"
FT DOMAIN 68..139
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DNA_BIND 28..48
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00320"
FT REGION 445..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 63195 MW; D680FD99F0F17498 CRC64;
MNKRGKYTTL NLEEKMKVLS RIEAGRSLKS VMDEFGISKS TFYDIKKNKK LILDFVLKQD
MPLAGAEKRK RTTGAKYGDV DDAVYMWYQR KRSAGVPVRG VELQAAAERF AQCFGRTDFK
ASTGWLFRFR NRHAIGNRKV CGEQVLSSAS ENVEPFRRKL YMLIKEEKLS LAQLYSGDET
DLFWKSMPEN IQASRKEICL PGRKINKERL SALLCANADG THKLKSIIIG KSKLPRSVKE
DTNTLPVIYK PSKDVWFTRE LFSEWFFQNF VPEVRHFQLS VLGFHEEDVR ALLLLDSSPV
HSSAESLTSE DGRIKCMFFP HNTSTLIQPM NQGVILSCKR LYRWKQLEES LVIFEESDDE
QDKGEKGVSK IKIYNIKSAI FNWAKSWDEV KQITIANAWE NLLYKKEPEY DIQGLEDGDY
RDILEKCGEL ETTLADDRVW FNGEDEEKGS PAKTKSGITK EVVQKGGGAE EQTAEFQLPA
VRESLDYLLD FVDVTPEFQR FRFTLKEMQQ EIIKKEFQSR IHSRIGSFLK PRPRVMKDSF
NMPSTSSN
//
