ID   A0A2U3YK77_LEPWE        Unreviewed;       331 AA.
AC   A0A2U3YK77;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Glycerophosphodiester phosphodiesterase 1 isoform X1 {ECO:0000313|RefSeq:XP_006744126.1};
GN   Name=GDE1 {ECO:0000313|RefSeq:XP_006744126.1};
OS   Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC   Leptonychotes.
OX   NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006744126.1};
RN   [1] {ECO:0000313|RefSeq:XP_006744126.1}
RP   IDENTIFICATION.
RC   TISSUE=Liver {ECO:0000313|RefSeq:XP_006744126.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the glycerophosphoryl diester phosphodiesterase
CC       family. {ECO:0000256|ARBA:ARBA00007277}.
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DR   RefSeq; XP_006744126.1; XM_006744063.2.
DR   AlphaFoldDB; A0A2U3YK77; -.
DR   STRING; 9713.A0A2U3YK77; -.
DR   GeneID; 102750757; -.
DR   KEGG; lww:102750757; -.
DR   CTD; 51573; -.
DR   OrthoDB; 2876171at2759; -.
DR   Proteomes; UP000245341; Unplaced.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd08573; GDPD_GDE1; 1.
DR   Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR   InterPro; IPR030395; GP_PDE_dom.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   PANTHER; PTHR46320; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1; 1.
DR   PANTHER; PTHR46320:SF1; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1; 1.
DR   Pfam; PF03009; GDPD; 1.
DR   SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR   PROSITE; PS51704; GP_PDE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT   DOMAIN          65..331
FT                   /note="GP-PDE"
FT                   /evidence="ECO:0000259|PROSITE:PS51704"
SQ   SEQUENCE   331 AA;  37717 MW;  44549BFEEC186EA3 CRC64;
     MWLWEEQGGL LGPFSFLLLL LLLVTRSPFN ACLFTGSLYL LLRLFSFEPV PSRRALQVLK
     PRDRVSAIAH RGGSHDAPEN TLAAIRQAAK NGATGVELDI EFTSDGIPVL MHDNTVDRTT
     DGTGRLCDLT FEQIRKLNPA ANHRLRNDFP DEKIPTLREA VAECLNYNLT IFFDVKGHAN
     MATDALKKIY KEFPQLYNNS IVCSFLPEVI YKMRQTDQNV VTALTHRPWS LSHTGDGKPR
     YDVFWKQSMF AVMDILLDWS MHNILWYLCG ISAFLIQKDF VSPDYLKKWS AKGIQVVAWT
     VNTFDEKSYY ESHLGSSYIT DSMLEDCASQ F
//