ID   A0A2U3YKS6_LEPWE        Unreviewed;       337 AA.
AC   A0A2U3YKS6;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2021, sequence version 2.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Quinone oxidoreductase PIG3 {ECO:0000313|RefSeq:XP_006744331.2};
GN   Name=TP53I3 {ECO:0000313|RefSeq:XP_006744331.2};
OS   Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC   Leptonychotes.
OX   NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006744331.2};
RN   [1] {ECO:0000313|RefSeq:XP_006744331.2}
RP   IDENTIFICATION.
RC   TISSUE=Liver {ECO:0000313|RefSeq:XP_006744331.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_006744331.2; XM_006744268.2.
DR   AlphaFoldDB; A0A2U3YKS6; -.
DR   STRING; 9713.A0A2U3YKS6; -.
DR   KEGG; lww:102742320; -.
DR   OrthoDB; 2598390at2759; -.
DR   Proteomes; UP000245341; Unplaced.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd05276; p53_inducible_oxidoreductase; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR014189; Quinone_OxRdtase_PIG3.
DR   NCBIfam; TIGR02824; quinone_pig3; 1.
DR   PANTHER; PTHR48106:SF8; QUINONE OXIDOREDUCTASE PIG3; 1.
DR   PANTHER; PTHR48106; QUINONE OXIDOREDUCTASE PIG3-RELATED; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT   DOMAIN          15..333
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   337 AA;  36056 MW;  1DF15C6B16EF52FC CRC64;
     MSSENMLAVH FDKPGGPENL YLTEVAKPSP VEGEVLLKVA ASALNRADLL QRQGQYAPPP
     GASSILGLEA SGHIAELGPA CRGHWKIGDP AMVLLPGGGQ AQYVTVPEEF LMPIPAGLTL
     SQAAAIPEAW LTAFQLLHLL GNVQAGDFVL IHAGSSGVGT AAIQLTRMAG AIPLVTAGSQ
     HKLQMAEKLG AAAGFNYKEE DFSEATLKFT KGAGVNLILD CIGGSYWEKN VSCLALDGRW
     ILYGLMGGTD VSGPLFSKLL FKRGSLITTL LRSRDKKYKQ RLVEAFTKQI LPNFSTESPQ
     RLLPVLDRVY PVAAIQEAHA YMESNRNVGK IVLELPQ
//