ID   A0A2U3YMD5_LEPWE        Unreviewed;       135 AA.
AC   A0A2U3YMD5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Helix-loop-helix protein 2 {ECO:0000313|RefSeq:XP_006744891.1};
GN   Name=NHLH2 {ECO:0000313|RefSeq:XP_006744891.1};
OS   Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC   Leptonychotes.
OX   NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006744891.1};
RN   [1] {ECO:0000313|RefSeq:XP_006744891.1}
RP   IDENTIFICATION.
RC   TISSUE=Liver {ECO:0000313|RefSeq:XP_006744891.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_006744891.1; XM_006744828.2.
DR   AlphaFoldDB; A0A2U3YMD5; -.
DR   STRING; 9713.A0A2U3YMD5; -.
DR   GeneID; 102742910; -.
DR   KEGG; lww:102742910; -.
DR   CTD; 4808; -.
DR   OrthoDB; 5403650at2759; -.
DR   Proteomes; UP000245341; Unplaced.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd19702; bHLH_TS_HEN2; 1.
DR   Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR040238; TAL-like.
DR   PANTHER; PTHR13864:SF19; HELIX-LOOP-HELIX PROTEIN 2; 1.
DR   PANTHER; PTHR13864; T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT   DOMAIN          77..129
FT                   /note="BHLH"
FT                   /evidence="ECO:0000259|PROSITE:PS50888"
FT   REGION          1..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   135 AA;  14958 MW;  129D8BF23E700AAE CRC64;
     MMLSPDQAAD SDHPSSAHSD PESLGGADAK VLGSVSDLEP VEEAEGDGKG GSRAALYPHP
     QQLSREEKRR RRRATAKYRS AHATRERIRV EAFNLAFAEL RKLLPTLPPD KKLSKIEILR
     LAICYISYLN HVLDV
//