ID A0A2U3YND7_LEPWE Unreviewed; 549 AA.
AC A0A2U3YND7;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Myotubularin-related protein 9 {ECO:0000313|RefSeq:XP_006745237.1};
GN Name=MTMR9 {ECO:0000313|RefSeq:XP_006745237.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006745237.1};
RN [1] {ECO:0000313|RefSeq:XP_006745237.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006745237.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
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DR RefSeq; XP_006745237.1; XM_006745174.2.
DR AlphaFoldDB; A0A2U3YND7; -.
DR STRING; 9713.A0A2U3YND7; -.
DR GeneID; 102729770; -.
DR KEGG; lww:102729770; -.
DR CTD; 66036; -.
DR OrthoDB; 5474662at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR CDD; cd13211; PH-GRAM_MTMR9; 1.
DR CDD; cd14536; PTP-MTMR9; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR InterPro; IPR030564; Myotubularin_fam.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR PANTHER; PTHR10807:SF56; MYOTUBULARIN-RELATED PROTEIN 9; 1.
DR Pfam; PF06602; Myotub-related; 1.
DR Pfam; PF21098; PH-GRAM_MTMR6-like; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT DOMAIN 123..498
FT /note="Myotubularin phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51339"
FT COILED 508..542
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 549 AA; 63626 MW; C3F7D21D5335AF6E CRC64;
MEFAELIKTP RVDNVVLHRP FYPAVEGTLC LTGHHLILSS RQDNTEELWL LHSNIDAIDK
RFVGPLGTII IKCKDFRIIQ LDIPGMEECL NIASSIEALS TLDSITLMYP FFYRPMFEVI
EDGWHSFLPE QEFELYSSAT SEWRLSYVNK EFAVCPSYPP IVIVPRSIDD EALRKVAMFR
HGGRFPVLSY YHKKNGMVIM RSGQPLTGTN GRRCKEDEKL INATLRAGKR GYIIDTRSLN
VAQQARAKGG GFEQEAHYPQ WRRIHKSIER YHILQESLIK LVEACNDQTH NMDRWLGRLE
ASNWLTHIKE ILTTACLAAQ CIDREGASIL IHGTEGTDST LQVTSLAQII LEPRSRTIRG
FEALIEREWL QAGHPFQQRC AQSAYCNSKQ KWESPVFLLF LDCVWQILRQ FPCSFEFNEN
FLIMLFEHAY ASQFGTFLGN NESERCKLKL QQKTMSLWSW VNRPSELRKF TNPLFEANNL
VIWPSVAPQS LQLWEGIFLR WNRSSKYLDE AYEEMVNIIE YNKELQAKVN VLRRQLAELE
TEDGMQESP
//
