ID A0A2U3YUK8_LEPWE Unreviewed; 374 AA.
AC A0A2U3YUK8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Serpin B8 isoform X2 {ECO:0000313|RefSeq:XP_006747407.1, ECO:0000313|RefSeq:XP_030874064.1};
GN Name=SERPINB8 {ECO:0000313|RefSeq:XP_006747407.1,
GN ECO:0000313|RefSeq:XP_030874064.1, ECO:0000313|RefSeq:XP_030874065.1,
GN ECO:0000313|RefSeq:XP_030874066.1, ECO:0000313|RefSeq:XP_030874067.1,
GN ECO:0000313|RefSeq:XP_030874068.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006747407.1};
RN [1] {ECO:0000313|RefSeq:XP_006747407.1, ECO:0000313|RefSeq:XP_030874064.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006747407.1,
RC ECO:0000313|RefSeq:XP_030874064.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_006747407.1; XM_006747344.2.
DR RefSeq; XP_030874064.1; XM_031018204.1.
DR RefSeq; XP_030874065.1; XM_031018205.1.
DR RefSeq; XP_030874066.1; XM_031018206.1.
DR RefSeq; XP_030874067.1; XM_031018207.1.
DR RefSeq; XP_030874068.1; XM_031018208.1.
DR STRING; 9713.A0A2U3YUK8; -.
DR GeneID; 102746629; -.
DR KEGG; lww:102746629; -.
DR CTD; 5271; -.
DR OrthoDB; 3218836at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR Gene3D; 2.10.310.10; Serpins superfamily; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR PANTHER; PTHR11461:SF166; SERPIN B8; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000245341}.
FT DOMAIN 13..374
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 374 AA; 42351 MW; 826001CE745FD482 CRC64;
MEDLHEANGR FAINLLKMLG EEDSSRNVFF SPLSISSALA MVFMGAKGNT ATQMSQALCL
NRGGDIHQGF RSLLTEVNKS GTQYLLRTAN RLFGEKTCDF LPAFRESCQK FYEAELEELS
FAADTEECRR HINDWVTERT EGKISEILGA GTVDPLTKLV LVNAVYFNGK WNEQFDRKYT
RGMPFKINQE KKTVQMMFKL AKFNLGYVDE VHAQVLELPY VGQELSMVIV LPDDNADLAL
VEKALTYEKF RAWTNPEKMT KDKVQVFLPR LKLEESYDLE SFLRSLGMTD AFEEAKADFS
GMSAKKNVPM SKVAHKCFVE VNEEGTEAAG ATAVVRNARS SRPEPRFCAD HPFLFFITHH
NTKSILFCGR FCSP
//
