ID   A0A2U3Z2X3_LEPWE        Unreviewed;       507 AA.
AC   A0A2U3Z2X3;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Vascular endothelial zinc finger 1 isoform X2 {ECO:0000313|RefSeq:XP_006750334.1};
GN   Name=VEZF1 {ECO:0000313|RefSeq:XP_006750334.1};
OS   Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC   Leptonychotes.
OX   NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006750334.1};
RN   [1] {ECO:0000313|RefSeq:XP_006750334.1}
RP   IDENTIFICATION.
RC   TISSUE=Liver {ECO:0000313|RefSeq:XP_006750334.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_006750334.1; XM_006750271.2.
DR   AlphaFoldDB; A0A2U3Z2X3; -.
DR   GeneID; 102725674; -.
DR   CTD; 7716; -.
DR   OrthoDB; 4067936at2759; -.
DR   Proteomes; UP000245341; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 5.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   PANTHER; PTHR16515:SF46; FINGER PROTEIN, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR16515; PR DOMAIN ZINC FINGER PROTEIN; 1.
DR   Pfam; PF00096; zf-C2H2; 4.
DR   SMART; SM00355; ZnF_C2H2; 6.
DR   SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 5.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 5.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245341};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT   DOMAIN          74..101
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          174..201
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          202..226
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          232..260
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   DOMAIN          261..288
FT                   /note="C2H2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50157"
FT   REGION          140..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        140..162
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   507 AA;  55067 MW;  D25EE4D23BC9C174 CRC64;
     MEANWTAFLF QAHEASHHQQ QAAQNSLLPL LSSAVEPPDQ KPLLPIPITQ KPQAAPETLK
     DAIGIKKEKP KTSFVCTYCS KAFRDSYHLR RHESCHTGIK LVSRSKKTPT TVVPLISTIA
     GDSSRTSLVS TIAGILSTVT TSSSGTNPSS SASTTAMPVT QSVKKPSKPV KKNHACEMCG
     KAFRDVYHLN RHKLSHSDEK PFECPVCNQR FKRKDRMTYH VRSHEGGITK PYTCSVCGKG
     FSRPDHLSCH VKHVHSTERP FKCQTCTAAF ATKDRLRTHM VRHEGKVSCN ICGKLLSAAY
     ITSHLKTHGQ SQSINCNTCK QGISKTCMSE EAGSQKQQQQ HVTSWPGKQV ETLRLWEEAV
     KARKKEAANL CQTSTAATTP VTLTTPFNIT SSVSSGTMSN PVTVAAAMSM RSPVNVSSAV
     NITSPMNIGH PVTITSPLSM TSPLTLTTPV NLPTPVTAPV NIAHPVTITS PMNLPTPMTL
     AAPLNIAMRP VESMPFLPQA LPTSPPW
//