ID A0A2U3Z4S1_LEPWE Unreviewed; 299 AA.
AC A0A2U3Z4S1;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
GN Name=LOC102748439 {ECO:0000313|RefSeq:XP_006750989.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006750989.1};
RN [1] {ECO:0000313|RefSeq:XP_006750989.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006750989.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}.
CC -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC {ECO:0000256|RuleBase:RU362056}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362056}.
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DR RefSeq; XP_006750989.1; XM_006750926.2.
DR AlphaFoldDB; A0A2U3Z4S1; -.
DR STRING; 9713.A0A2U3Z4S1; -.
DR GeneID; 102748439; -.
DR KEGG; lww:102748439; -.
DR OrthoDB; 2874223at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004156; OATP.
DR NCBIfam; TIGR00805; oat; 1.
DR PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR PANTHER; PTHR11388:SF14; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1; 1.
DR Pfam; PF03137; OATP; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU362056};
KW Membrane {ECO:0000256|RuleBase:RU362056};
KW Reference proteome {ECO:0000313|Proteomes:UP000245341};
KW Transmembrane {ECO:0000256|RuleBase:RU362056};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362056};
KW Transport {ECO:0000256|RuleBase:RU362056}.
FT TRANSMEM 37..61
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 73..101
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 121..145
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 194..216
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 228..254
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 266..284
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT NON_TER 1
FT /evidence="ECO:0000313|RefSeq:XP_006750989.1"
SQ SEQUENCE 299 AA; 33020 MW; 8C348D4B7C0E9736 CRC64;
NNSFFQAELC QKHWQDLPPS KCHSTTQDSQ KETSSMWALM VVGQLLAGVG TVPIQPFGIS
YVDDFSEPSN SPLYISILFA ISVFGPAFGY LLGSVMLQIF VDYGRVDTAA VNLSPGDPRW
IGAWWLGLLI SSASLVLTSF PFFFFPRTML REAERSPAIV DEARKMDEVK PRSSLVDFIK
RFPRIFLRLL MNPLFMLVVL AQCTFSSVIA GLSTFLNKFL EKQYGASAAY ANFLIGAVNL
PAAALGMLFG GILMKRFVFS LQTIPRVAAT IITISMVLCA PLFFMGCSTP TVAEVYPTR
//
