ID A0A2U3Z5P6_LEPWE Unreviewed; 285 AA.
AC A0A2U3Z5P6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=POC1 centriolar protein homolog A {ECO:0000256|ARBA:ARBA00039725};
GN Name=LOC102744103 {ECO:0000313|RefSeq:XP_006751053.1};
OS Leptonychotes weddellii (Weddell seal) (Otaria weddellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae;
OC Leptonychotes.
OX NCBI_TaxID=9713 {ECO:0000313|Proteomes:UP000245341, ECO:0000313|RefSeq:XP_006751053.1};
RN [1] {ECO:0000313|RefSeq:XP_006751053.1}
RP IDENTIFICATION.
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_006751053.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body
CC {ECO:0000256|ARBA:ARBA00004120}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriole
CC {ECO:0000256|ARBA:ARBA00004114}.
CC -!- SIMILARITY: Belongs to the WD repeat POC1 family.
CC {ECO:0000256|ARBA:ARBA00037984}.
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DR RefSeq; XP_006751053.1; XM_006750990.2.
DR AlphaFoldDB; A0A2U3Z5P6; -.
DR STRING; 9713.A0A2U3Z5P6; -.
DR GeneID; 102744103; -.
DR KEGG; lww:102744103; -.
DR OrthoDB; 2575345at2759; -.
DR Proteomes; UP000245341; Unplaced.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44019:SF2; POC1 CENTRIOLAR PROTEIN HOMOLOG A; 1.
DR PANTHER; PTHR44019; WD REPEAT-CONTAINING PROTEIN 55; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000245341};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 15..56
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 57..88
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 99..140
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 141..182
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 183..224
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 225..266
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT NON_TER 285
FT /evidence="ECO:0000313|RefSeq:XP_006751053.1"
SQ SEQUENCE 285 AA; 31626 MW; D54967AADDFD5CE1 CRC64;
MAAPCPEDPS LERHFKGHRD AVTCVDFSLN TKQLASGSMD SCLMVWHMKP QSRAYRFAGH
KDAVTCVNFS PSGHLLASGS RDKTVRIWIP NVKGESTVFR AHTATVRSIH FCSDGQSFVT
ASDDKTVKVW STHRQKFLFS LSQHINWVRC ARFSPDGRLI VSASDDKTVK LWDKTSRECV
HSYCEHGGFV TFVDFHPSGT CIAAGGMDNT VKVWDVRTHR LLQHYQLHSA AVNALSFHPS
GNYLLTASSD STLKILDLME GRLLYTLHGH QVRASAWCCG VEGGG
//
