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Database: UniProt
Entry: A0A2U3ZZA5_TURTR
LinkDB: A0A2U3ZZA5_TURTR
Original site: A0A2U3ZZA5_TURTR 
ID   A0A2U3ZZA5_TURTR        Unreviewed;      3077 AA.
AC   A0A2U3ZZA5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   10-FEB-2021, entry version 12.
DE   SubName: Full=centromere protein F isoform X1 {ECO:0000313|RefSeq:XP_019774073.1};
GN   Name=CENPF {ECO:0000313|RefSeq:XP_019774073.1};
OS   Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Delphinidae; Tursiops.
OX   NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019774073.1};
RN   [1] {ECO:0000313|RefSeq:XP_019774073.1}
RP   IDENTIFICATION.
RC   TISSUE=Spleen {ECO:0000313|RefSeq:XP_019774073.1};
RG   RefSeq;
RL   Submitted (OCT-2020) to UniProtKB.
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DR   RefSeq; XP_019774073.1; XM_019918514.1.
DR   GeneID; 101333752; -.
DR   CTD; 1063; -.
DR   OMA; YNAQLVQ; -.
DR   Proteomes; UP000245320; Genome assembly.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245320}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          2094..2233
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2277..2415
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2932..2976
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          188..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          460..497
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          804..828
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1364..1385
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1664..1688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2854..3077
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          280..384
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          509..706
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          718..759
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          839..873
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          899..957
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          969..989
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1036..1056
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1089..1109
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1118..1159
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1203..1230
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1285..1326
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1403..1423
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1546..1566
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1571..1616
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1789..1851
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1885..1905
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1927..2062
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2070..2097
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2105..2160
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2168..2248
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2287..2314
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2319..2339
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2343..2458
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2466..2486
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2490..2566
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2592..2647
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2652..2792
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2799..2826
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        192..232
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        475..497
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1370..1385
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2854..2895
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2914..2934
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2962..2976
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2992..3043
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3077 AA;  353447 MW;  B8CE96CBFA4ADED2 CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKVENEKA
     EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNTSKKQ IEKLEQELKR
     CKSELERSQQ AAQSADVSMS PCTTPQKIFA TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
     LEAEVKALQA KKASQATPQS TMNHRDIARH QASSSVFSWQ QEKTPSRLSS SALKTPIRRD
     FSASSFSGEQ EVTLSRSTLQ IGNRDANSSF CDNSSNSHLL DQFKAQNQEL RSKISELELR
     LQGQEREMKG QVNKLQELQL QVEKAKVELN EKEKVLNKSR DELVRTTAQY DQASTKCIAL
     EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQEFTQMKAK
     LTQELQQAKN MHNILQAELD KATSVKHQLE KKLEEFKEKF SRTEQTLQAS QTKENELRRS
     SEEMKRENSL LKSQSEQRAR EVCHLEEELK KAKQRLSQSQ NFAEEMRAKN TSQETMLRDL
     QEQIKQQENS LTLEKLKLAL ADLEKQRDCS QDLLKKREHH IEQLNEKLSQ TERESEALLS
     ALELKKKEYE ELKEEKTLFS RWKSENEQLL NQMESEKESL QSKINHLETC LKTQQIKSHE
     YNERVRTLEM ERENLNVEIR NLHNVIDSKT AEAETQKQAY GELQQKAEFS DQKHEKEIEN
     MCLKISQLTG QVEDLEDKLQ SLSSEIMDKN QRYQDLHAES ESLRDLLKSR DSSAVTNESH
     QRSLLAFEQQ SAVNNSFANI IEEQESVPSE RSECHLETDQ SPKSSSMLQN RVVSLEFSLE
     SQKQMNSDLQ KQCEELVQIK GEIEENLMKA EQMHQSFVAE TSQRISKLQE DTSVHQNVVV
     ETLAALESKE RELQLLNEKL ETEQAEIQEL KKSNHLLQES LKELQLLSET LSLEKKEMSS
     IISLDKKDIE ELTQENGTLK EINATLTQEK MNLLQKTESF SNCIDERDKS ISELSDQYKQ
     ERLTLLQRCE ETGNAFRDLS EKYKAEQEKN SKLECLLNEC TSVCEDRENE LGQLKETFAR
     EHQAFVSQLA LAEERNQSLI LELETVQQAL RSEVTDIQSN SKREADSLKQ EIMTLKEEQS
     KMQQEVNALL QEKEHLMELM KTKHEHQHLE LEPIQDSVKV AERKINTRHV QLPMDLEVKD
     ASLDSYNAQL AQVETKVRNM ELKLQESEKE EYLQHELQIG GELETGDVQQ GTQSQDISGL
     GNFEIDPEEK YISVLHELST SQQDNAHLQC SLQTAMNKLD ELEKMCEALQ VEKLELISEL
     NDSRSECVTA TSKMAEEVGK LVNEVKILND ENGLLQGEFV KETPESEFGE QQDEQTSVSL
     NPLDDSNSYE HLTVSNKEVR MHFAELQEKF SSLQSEHKTL HDQHCQMSSK MSELQSYIDT
     LKAENSVLSM SLRNSQGDLV KEVMPGPGEK HFLSLSLSGV TDSPGNAIES SFYKDFLEHM
     GETSLLNNLD RTVLANQSSV EKVSCSSLEE ENLTEKEIPS APVRSVEELE TVCQMYLQSF
     KKLEEKIESQ GITKNKEIEE LERLLSSARE ELDCLRKQYL SENEQWQQKL TSVTAEMESK
     LAAEKKHTEH LTLELEVARL QLQGLDLSSR SLLGTDIDDA IRGGNDSCDI REPEDYTSET
     KERTPEHEIH QICEKDVQQD LSLEMEKITK TSAIKLIGEW SGEQSPETSH GTPVEDTTQG
     CSECISQLSL SGPDASVPMD FLENQVAIQN LQLQVKETSN ENLRLLHGIK ERDQKVESLL
     NEIKELDSKL NLQEVQLTTK IEACIELEKI VEELKKEKSD FSEKLESFSR DNQRVESSRG
     LTSNLEMGTD KLSHEGIEDE VAKVTDNWRE RCLSVENELQ RMKAERGSTE HHALSVEANL
     EVVQTEKLFL EKDNENKQKV INCLEEELLV VTSERDQLRG ELDTLSKENQ ELDQMSEKMK
     EKIQELESHQ DEYLHLQEQL QSLEKDSQAL SLVRSELENQ IRQLNKETKS LVRESESLQT
     KLSELEHEKQ TVTKALEAAL MEKGEVAVRL SSTQEEVHQL RKGIEKLRVR IEADEKKQLH
     ISEKLKESER RNDSLQDKVE TLERELHMAE ENQELVILDA ENSKAEVETL RTQMELMTES
     LKALDLDLVT IRSEKENLVK QLQEKQGQVS ELHTLLSSLK NVLEEKEREK IQMKEESKAV
     VEILQTQLKE LSEEVAALCD DQETWKAEEQ SLDSPVQEVH QLRNNIGKLK VHLDTNERKR
     LHILEKLKES EHQAALLKDT VENLERELEV SGKNQEHVIL EAEKSKAEVE TLKAKIEEMA
     PNLRALELDL VNTRSEKEDL TKELQKEQGR VSELETLNSS FENLLQEKEQ EKEQMKEESK
     AVVEILQTQL KELSEEVAAL CDDQETWKAE EQSLSSQVDS LEREKAQLLQ GLDEAKSNYM
     LLQSSVNGLI QEVEDGKQKL EKKDEETRIL KNHIQDQEQL VSKLSQMEGE QQLWEEQRTK
     LENLMVELEQ KTQVLQSKND TLQDTLEALQ NSSKDLEKEL QLTKMEKLSF VEKVNTMTVK
     ETELQKEMLA MVQKTTELKE EFSREKNRLT EDLKLVSEEM KSRKSQLEEL ILENSELKKS
     LDCVHKDQME KQGKMREEIA EYQLRLQEAE KKHQALLLDI NKQYEMEIQT YREKLTSKEE
     CLSSQKVEID LLKSSKEELN NSLKVTTEIL EELKKTKMEN LKYADKLKKE NDRAQGKIKL
     LIKSCKQLEE EKETLQKEVS RLEAAQEKQK AGTVVDANVD ELMTEMKELK ETLEEKTKEA
     DEYLDKYCSL LISHEKLEKA KEMLETQVAR LSSQQSKLNL RSSPSLNSVV PGPSPVPSAT
     EKKLSSGQNK ASGKRQRSGG IREDGGETTP STPEKFSKKS RKAVKSGIHP AEDAEDAEPE
     PEGLPEVVKK GFADIPTGKT SPYILRRTTM VTRTSPRLAA QKLAPSPLSL DKENLAETSK
     PTAGGSRSQK VKVTQQSPVD SGTALREPTT RSLSISNLPE RSSADSPREG LRAKQGRLAP
     SPEAGPESKG SENCRVQ
//
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