ID A0A2U4A071_TURTR Unreviewed; 3026 AA.
AC A0A2U4A071;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 10-FEB-2021, entry version 10.
DE SubName: Full=centromere protein F isoform X2 {ECO:0000313|RefSeq:XP_019774074.1};
GN Name=CENPF {ECO:0000313|RefSeq:XP_019774074.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019774074.1};
RN [1] {ECO:0000313|RefSeq:XP_019774074.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_019774074.1};
RG RefSeq;
RL Submitted (OCT-2020) to UniProtKB.
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DR RefSeq; XP_019774074.1; XM_019918515.1.
DR GeneID; 101333752; -.
DR CTD; 1063; -.
DR Proteomes; UP000245320; Genome assembly.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 2094..2233
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2277..2415
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2881..2925
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 188..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 460..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 804..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1364..1385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1664..1688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2803..3026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 280..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 509..706
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 718..759
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 839..873
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 899..957
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 969..989
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1036..1056
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1089..1109
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1118..1159
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1203..1230
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1285..1326
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1403..1423
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1546..1566
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1571..1616
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1789..1851
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1885..1905
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1927..2062
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2070..2097
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2105..2160
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2168..2248
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2287..2314
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2319..2339
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2343..2458
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2466..2486
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2490..2566
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2576..2596
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2601..2741
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2748..2775
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 192..232
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..497
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1370..1385
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2803..2844
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2863..2883
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2911..2925
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2941..2992
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3026 AA; 347376 MW; 7C6E258DD6F17A0C CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKVENEKA
EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNTSKKQ IEKLEQELKR
CKSELERSQQ AAQSADVSMS PCTTPQKIFA TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
LEAEVKALQA KKASQATPQS TMNHRDIARH QASSSVFSWQ QEKTPSRLSS SALKTPIRRD
FSASSFSGEQ EVTLSRSTLQ IGNRDANSSF CDNSSNSHLL DQFKAQNQEL RSKISELELR
LQGQEREMKG QVNKLQELQL QVEKAKVELN EKEKVLNKSR DELVRTTAQY DQASTKCIAL
EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQEFTQMKAK
LTQELQQAKN MHNILQAELD KATSVKHQLE KKLEEFKEKF SRTEQTLQAS QTKENELRRS
SEEMKRENSL LKSQSEQRAR EVCHLEEELK KAKQRLSQSQ NFAEEMRAKN TSQETMLRDL
QEQIKQQENS LTLEKLKLAL ADLEKQRDCS QDLLKKREHH IEQLNEKLSQ TERESEALLS
ALELKKKEYE ELKEEKTLFS RWKSENEQLL NQMESEKESL QSKINHLETC LKTQQIKSHE
YNERVRTLEM ERENLNVEIR NLHNVIDSKT AEAETQKQAY GELQQKAEFS DQKHEKEIEN
MCLKISQLTG QVEDLEDKLQ SLSSEIMDKN QRYQDLHAES ESLRDLLKSR DSSAVTNESH
QRSLLAFEQQ SAVNNSFANI IEEQESVPSE RSECHLETDQ SPKSSSMLQN RVVSLEFSLE
SQKQMNSDLQ KQCEELVQIK GEIEENLMKA EQMHQSFVAE TSQRISKLQE DTSVHQNVVV
ETLAALESKE RELQLLNEKL ETEQAEIQEL KKSNHLLQES LKELQLLSET LSLEKKEMSS
IISLDKKDIE ELTQENGTLK EINATLTQEK MNLLQKTESF SNCIDERDKS ISELSDQYKQ
ERLTLLQRCE ETGNAFRDLS EKYKAEQEKN SKLECLLNEC TSVCEDRENE LGQLKETFAR
EHQAFVSQLA LAEERNQSLI LELETVQQAL RSEVTDIQSN SKREADSLKQ EIMTLKEEQS
KMQQEVNALL QEKEHLMELM KTKHEHQHLE LEPIQDSVKV AERKINTRHV QLPMDLEVKD
ASLDSYNAQL AQVETKVRNM ELKLQESEKE EYLQHELQIG GELETGDVQQ GTQSQDISGL
GNFEIDPEEK YISVLHELST SQQDNAHLQC SLQTAMNKLD ELEKMCEALQ VEKLELISEL
NDSRSECVTA TSKMAEEVGK LVNEVKILND ENGLLQGEFV KETPESEFGE QQDEQTSVSL
NPLDDSNSYE HLTVSNKEVR MHFAELQEKF SSLQSEHKTL HDQHCQMSSK MSELQSYIDT
LKAENSVLSM SLRNSQGDLV KEVMPGPGEK HFLSLSLSGV TDSPGNAIES SFYKDFLEHM
GETSLLNNLD RTVLANQSSV EKVSCSSLEE ENLTEKEIPS APVRSVEELE TVCQMYLQSF
KKLEEKIESQ GITKNKEIEE LERLLSSARE ELDCLRKQYL SENEQWQQKL TSVTAEMESK
LAAEKKHTEH LTLELEVARL QLQGLDLSSR SLLGTDIDDA IRGGNDSCDI REPEDYTSET
KERTPEHEIH QICEKDVQQD LSLEMEKITK TSAIKLIGEW SGEQSPETSH GTPVEDTTQG
CSECISQLSL SGPDASVPMD FLENQVAIQN LQLQVKETSN ENLRLLHGIK ERDQKVESLL
NEIKELDSKL NLQEVQLTTK IEACIELEKI VEELKKEKSD FSEKLESFSR DNQRVESSRG
LTSNLEMGTD KLSHEGIEDE VAKVTDNWRE RCLSVENELQ RMKAERGSTE HHALSVEANL
EVVQTEKLFL EKDNENKQKV INCLEEELLV VTSERDQLRG ELDTLSKENQ ELDQMSEKMK
EKIQELESHQ DEYLHLQEQL QSLEKDSQAL SLVRSELENQ IRQLNKETKS LVRESESLQT
KLSELEHEKQ TVTKALEAAL MEKGEVAVRL SSTQEEVHQL RKGIEKLRVR IEADEKKQLH
ISEKLKESER RNDSLQDKVE TLERELHMAE ENQELVILDA ENSKAEVETL RTQMELMTES
LKALDLDLVT IRSEKENLVK QLQEKQGQVS ELHTLLSSLK NVLEEKEREK IQMKEESKAV
VEILQTQLKE LSEEVAALCD DQETWKAEEQ SLDSPVQEVH QLRNNIGKLK VHLDTNERKR
LHILEKLKES EHQAALLKDT VENLERELEV SGKNQEHVIL EAEKSKAEVE TLKAKIEEMA
PNLRALELDL VNTRSEKEDL TKELQKEQGR VSELETLNSS FENLLQEKEQ EKEQMKEESK
AVVEILQTQL KELSEEVAAL CDDQETWKAE EQSLSSQVDS LEREKAQLLQ GLDEAKSNYM
LLQSSVNGLI QEVEDGKQKL EKKDEETRIL KNHIQDQEQL VSKLSQMEGE QQLWEEQRTK
LENLMVELEQ KTQVLQSKND TLQDTLEALQ NSSKDLEKEL QLTKMEKLSF VEKSQLEELI
LENSELKKSL DCVHKDQMEK QGKMREEIAE YQLRLQEAEK KHQALLLDIN KQYEMEIQTY
REKLTSKEEC LSSQKVEIDL LKSSKEELNN SLKVTTEILE ELKKTKMENL KYADKLKKEN
DRAQGKIKLL IKSCKQLEEE KETLQKEVSR LEAAQEKQKA GTVVDANVDE LMTEMKELKE
TLEEKTKEAD EYLDKYCSLL ISHEKLEKAK EMLETQVARL SSQQSKLNLR SSPSLNSVVP
GPSPVPSATE KKLSSGQNKA SGKRQRSGGI REDGGETTPS TPEKFSKKSR KAVKSGIHPA
EDAEDAEPEP EGLPEVVKKG FADIPTGKTS PYILRRTTMV TRTSPRLAAQ KLAPSPLSLD
KENLAETSKP TAGGSRSQKV KVTQQSPVDS GTALREPTTR SLSISNLPER SSADSPREGL
RAKQGRLAPS PEAGPESKGS ENCRVQ
//
