ID A0A2U4A6M8_TURTR Unreviewed; 470 AA.
AC A0A2U4A6M8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=N(6)-adenine-specific DNA methyltransferase METTL4 {ECO:0000313|RefSeq:XP_004320794.2, ECO:0000313|RefSeq:XP_019776359.1};
GN Name=METTL4 {ECO:0000313|RefSeq:XP_004320794.2,
GN ECO:0000313|RefSeq:XP_019776359.1, ECO:0000313|RefSeq:XP_019776360.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019776359.1};
RN [1] {ECO:0000313|RefSeq:XP_004320794.2, ECO:0000313|RefSeq:XP_019776359.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_004320794.2,
RC ECO:0000313|RefSeq:XP_019776359.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MT-A70-like family. {ECO:0000256|PROSITE-
CC ProRule:PRU00489}.
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DR RefSeq; XP_004320794.2; XM_004320746.3.
DR RefSeq; XP_019776359.1; XM_019920800.2.
DR RefSeq; XP_019776360.1; XM_019920801.2.
DR STRING; 9739.ENSTTRP00000007812; -.
DR GeneID; 101322660; -.
DR OrthoDB; 179166at2759; -.
DR Proteomes; UP000245320; Chromosome 13.
DR GO; GO:0140640; F:catalytic activity, acting on a nucleic acid; IEA:UniProt.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR007757; MT-A70-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12829:SF4; N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4; 1.
DR PANTHER; PTHR12829; N6-ADENOSINE-METHYLTRANSFERASE; 1.
DR Pfam; PF05063; MT-A70; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51143; MT_A70; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|RefSeq:XP_004320794.2,
KW ECO:0000313|RefSeq:XP_019776359.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW Transferase {ECO:0000313|RefSeq:XP_004320794.2,
KW ECO:0000313|RefSeq:XP_019776359.1}.
SQ SEQUENCE 470 AA; 53718 MW; 824A15334E3951E8 CRC64;
MSVVRELSPG WLLDHLSFIN KISYELHQHH EPCCSKNEPT SSVHLDTLHV DSVSSFGASA
TCIASTTKPE NDDGGNCEMF IQKYVFRSEL FDVTKPYITS AIHKECQQSN EKEDLVNDVK
KEISISVNGK KRKRCVVFNQ GELDAMEYHT KIRGLILDGS SQLIQEGLRS GFLHPLYEKR
DKYTEPITLP LDTCNLSELC EMAKHLPSLN EMELQTLQLM DDDISVTEQD LFSRIVENNS
SFTKMITLMG QKYLLPPKSS FLLSDISCMY PLLSCKKTYD VIVIDPPWQN KSVKRSNRYS
YLSPLQIKQI PIPKLAAPNC LVVTWVTNRQ KHLRFVKEEL YPSWSVEIVA EWHWVKITSS
GEFVFPLDSP HKKPYEGLIL GRVREKAALP LRNADVKELP IPDHKLIVSV PCTLHSHKPP
LAEVLKDYIK PEGECLELFA RNLQPGWTSW GNEVLKFQHV DYFVALESKS
//
