ID   A0A2U4A9X4_TURTR        Unreviewed;       260 AA.
AC   A0A2U4A9X4;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   07-OCT-2020, sequence version 2.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|ARBA:ARBA00020634};
DE   AltName: Full=Mediator complex subunit 6 {ECO:0000256|ARBA:ARBA00031259};
GN   Name=MED6 {ECO:0000313|RefSeq:XP_019777559.2};
OS   Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Delphinidae; Tursiops.
OX   NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019777559.2};
RN   [1] {ECO:0000313|RefSeq:XP_019777559.2}
RP   IDENTIFICATION.
RC   TISSUE=Spleen {ECO:0000313|RefSeq:XP_019777559.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 6 family.
CC       {ECO:0000256|ARBA:ARBA00007526}.
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DR   RefSeq; XP_019777559.2; XM_019922000.2.
DR   AlphaFoldDB; A0A2U4A9X4; -.
DR   STRING; 9739.ENSTTRP00000008133; -.
DR   Proteomes; UP000245320; Chromosome 2.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 3.10.450.580; Mediator complex, subunit Med6; 1.
DR   InterPro; IPR007018; Mediator_Med6.
DR   InterPro; IPR016820; Mediator_Med6_met/pln.
DR   InterPro; IPR038566; Mediator_Med6_sf.
DR   PANTHER; PTHR13104; MED-6-RELATED; 1.
DR   PANTHER; PTHR13104:SF0; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6; 1.
DR   Pfam; PF04934; Med6; 1.
DR   PIRSF; PIRSF023869; Mediator_MED6_meta/pln; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REGION          194..242
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        202..226
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   260 AA;  30111 MW;  ECE672373DEC0378 CRC64;
     MAAVDIRDNL LGISWVDSSW IPILNSGSVL DYFSERSNPF YDRTCNNEVV KMQRLTLEHL
     NQMVGVEYIL LHAQEPILFI IRKQQRQSPT QVIPLADYYI IAGVIYQAPD LGSVINSRVL
     TVVHGIQSAF DEAMSYCRYH PSKGYWWHFK DHEEQDKVKP KVKRKEEPSS IFQRQRVDAL
     LLDLRQKFPP RFVQQKSGEK PVPVDQTKKE AEPIPETVKS EEKETTKNVQ QTVGTKGPPE
     KRMRLHTEAL MVHLFQDIDP
//