ID A0A2U4ANM7_TURTR Unreviewed; 2967 AA.
AC A0A2U4ANM7;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 07-OCT-2020, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Zinc finger ZZ-type and EF-hand domain-containing protein 1 isoform X8 {ECO:0000313|RefSeq:XP_019782424.2};
GN Name=ZZEF1 {ECO:0000313|RefSeq:XP_019782424.2};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019782424.2};
RN [1] {ECO:0000313|RefSeq:XP_019782424.2}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_019782424.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_019782424.2; XM_019926865.2.
DR STRING; 9739.ENSTTRP00000000550; -.
DR Proteomes; UP000245320; Chromosome 20.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08667; APC10-ZZEF1; 1.
DR CDD; cd02249; ZZ; 1.
DR CDD; cd02343; ZZ_EF; 1.
DR Gene3D; 3.30.60.90; -; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR004939; APC_su10/DOC_dom.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR InterPro; IPR040099; ZZEF1.
DR InterPro; IPR047052; ZZEF1_APC10.
DR InterPro; IPR041986; ZZEF1_ZZ.
DR PANTHER; PTHR22772; NOVEL ZZ TYPE ZINC FINGER DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22772:SF4; ZINC FINGER ZZ-TYPE AND EF-HAND DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF03256; ANAPC10; 1.
DR Pfam; PF00569; ZZ; 2.
DR SMART; SM01337; APC10; 1.
DR SMART; SM00054; EFh; 1.
DR SMART; SM00291; ZnF_ZZ; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS51284; DOC; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 111..146
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 226..405
FT /note="DOC"
FT /evidence="ECO:0000259|PROSITE:PS51284"
FT DOMAIN 1778..1833
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT DOMAIN 1827..1882
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1455..1529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1969..2083
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2431..2461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1499..1519
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1976..1991
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2007..2026
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2441..2461
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2967 AA; 331675 MW; A48F0F693B9938A1 CRC64;
MGNAPSHSSE DEAAAAGGEA WGPHQDWAKD SGTTPGPGPA APALPPAAAL LEPARLREAA
AALRPAPPYE SLVSRHHGAL LRWLEERLGR GEESVTLEQF GELLEARGAG FSGERFEEAF
AQFDAEGDGT VDAENMLEAL KNSSGANLQG ELSHIIRQLQ ACSLVPGFID IFSESKEGLD
VHSSMILRFL HRNRLSSTVI PYPMLDHCNN MSTMRASVLK DSLDQLVQKE KESPGDLTRS
PEMDKLKSVA KCYTYIETSS NPADIDKMTN GETSSYWQSD GSARSHWIRL KMKPDVVLRH
LSIAVAATDQ SYMPQQVTVA VGRSASDLQE VRDVHIPSNV TGYVTLLENA NISQLYVQIN
IKRCLSDGCD TRIHGLRAVG FQRVKKSGVS VSDASAIWYW SLLTSLVTAS METNPAFVQT
VLRNTQKALQ HMPPLSLSPG STDFSTFLSP NVLEEVDSFL IRITSCSSTP EVELTLLAFA
LARGSVAKVL SSLCTVTDHL DTHYDASSLI SSMASVRQNL LLKYGKPLQL ILQACDVKGK
EEKSGPENLL VEPWTRDGFL TETGKTRAST IFSTGTESAF QVTQIRIMVR RGGIGAQCGL
VFAYNSSSDK FHAEEHFKRF EKYDKWKLQE FRQFVKSRIG CPSDNLGEDD PIGWFELEEE
WDEADVKLQQ CRVAKYLMVK FLCTRQESAE RLGVQGLSIS GYLRPARAEA EQSIVRTHCR
KGVEESVCGA TLLLRTLQFI QQLAHDLVQQ KESGLKYRSF LDFAGLDLQI FWDFYSKLKQ
NPREECICAQ TLLLQLLQSC FSVLQGDVSA TSEDAKAPSM SRRRVEAAKE LYTHLCDVVD
RVDGDSAPME ILKQEVRNTL LNGAAVFFPD RQTRRDHLFT MMNVTEQEHK QSLQLTFRSL
CTYFSDKDPG GLLLLPEKGD LADTDISEVL AVMSTLLSVA ARECELLMVD GAQGEVGSVL
FSLFWSVQGS LLSWCYLQLK STDSGAKDLA ADLIEKYVGQ FLARMRVILE SLLSQYSGKT
VVEKLCNSVF SMAARQLVIF LLDFCTLDIS HCTLLREFSA LTELLKELCS DPDGGLNKLD
VETWQQERPV VLHTWTKESA HNYENNCHEV SVFVSPGATY FEVEFDERCE TEKRYDYLEF
TDARGGKTRY DTKVGTDKWP KKVTFKAGPR LQFLFHSDSS NNEWGYKFTV TAYGLPDVAV
SWGLDLQLLV SRLMGRLASQ CMALKSVHQL GSNMAIPQAK MALVLNSPLW KPVFRHQICP
ELGLEASWPT HPPQDNKEVK NIPDDPCHQF LLDFAQSDPA QNFCGPYSEL FKGFIQACRK
QAPKTDIVAG STIDQAVNAT FAALVYRTPD LYEKLQKYVN SGGKTALSEE FAQVYSLADG
IRIWMLEMKQ KSLMSLGNEA EEQRGPEAAE VNPESLAKEC IQKSLLLLKF LPMGVSSKEG
CDKLVAVDDT DHLRPLDKRQ RTSSVVEEHF QASTSPTKAA PPAVEDRSPG LDVQPTLPPS
SGAPATEVSS ATAEEPSSPS TPTRRPPFTR GRLRLLSFRS VEEARPLPTV KEKYPVLKDA
MDFIKDQSLS HESVVKVLSL RKAQARSILE VLRIIQCCTE SLGQPHCFHP PFILFLLELL
TCQKEFTNYF GHLEGCGADL HKEIRDTYYQ FVLFLVKAVK GFSNVNDRSL LPALSCVQTA
LLHLLDMGWE PGDLTFFVDI QLPDLLMKMS QENISVHDSV ISQWSEEDEL ADAKQNSEWM
DECQDGMFEA WYEKIAQEDP EKQRKMHMFI ARYCDLLNVD ISCDGCDEIA PWHRYRCLQC
SDMDLCKTCF LGGVKPEGHG DDHEMVNMEF TCDHCQGLII GRRMNCNVCD DFDLCYGCYA
AKKYSYGHLP THSITAHPMV TIRISDRQRL IQPYIHNYSW LLFAALALYS THLASAEDVD
GEKLDPQARS SAATLRSQCM QLVGDCLMKA HQGKGLKALA LLGILPDGDS TSEKQAPPVA
VPTQTSEEQP EKKAIQAAVE PADAGPFVHR SGKRDAPKEA RPLDCKQRSK AGGAASLLKG
PSCQTQISDS PADACAPTEL PDAENAEASS QKPIEEKAVT PSPEQVFAEC SQKRILGLLA
AMLPPLNSDP TVPLIDLEHV LPLMFQVVIS NAGHLNETYH LTLGLLGQLI IRLSPVEVDA
AVTKVLSAKH NLFAAGDSSI VPDGWKTTHL LFSLGAVCLD SRVGLDWACS MAEILRSLNS
APLWRDVIAT FTDHCIKQLP FQLKHTNIFT LLVLVGFPQV LCAGTRCVYM DNANEPHNVI
ILKHFTEKNR AVIVNVKTRK RKTVKDYQLV QKGGGPECSN SQAQLSQYSQ HFAFIASHLL
QTSMDSHCPE AVEATWVLSL ALKGLYKTLK AHGFEETHAT FLQTDLLKLL VKKCSKGTGF
SKTWLLRDLE ILSIMLYSSK KEISTLAEHG ELELDERGDQ EEEVERSVSS PGEPEQKKLD
PLESLDEPTR ICFLMAHDAL NAPLHILRAI YELQMKRTDS FFLEVQKRFD GDELTTDERI
RTLAQRWQPS RSLRLDEQSA KAVDTDMIIL PCLSRPARCD QATTESNPVT QKLISSTESE
LQQSYAKQRR SKSAALLHKE LNCKSKRAVR DYLFRVNEAT AVLYARHVLA SLLAEWPGHV
PVSEDILELS GPAHMTYILD MFMQLEEKHQ WEKILQKVLQ GCRESMLGTM ALAACQFMEE
PGMEVQVRES KHPYNNNTNF EDKVHIPGAI YLSIKFDPQC NTEEGCDELA MSSSSDFQQD
RHNFSGPQQK WKDFELPGDT LYYRFTSDMS NTEWGYKFTV TAGHLGRFQT GFEILKQMLS
EERVVPHLPL AKIWEWLVSV ACRQTGHQRL KAIHLLLRIV RCCTHSDLCD LMLLKPLWQL
FTQMEYSLFE DVTQPGILLP LHRALTELFF VTENRAQELG LLQDYLLALT TDDHLLRCAA
QALQNIAAIS LAINYPNKAT RLWNVEC
//
