ID A0A2U4ASJ5_TURTR Unreviewed; 1130 AA.
AC A0A2U4ASJ5;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=TBC1 domain family member 1 isoform X8 {ECO:0000313|RefSeq:XP_019783916.1};
GN Name=TBC1D1 {ECO:0000313|RefSeq:XP_019783916.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019783916.1};
RN [1] {ECO:0000313|RefSeq:XP_019783916.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_019783916.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_019783916.1; XM_019928357.2.
DR AlphaFoldDB; A0A2U4ASJ5; -.
DR GeneID; 101328062; -.
DR OrthoDB; 2908929at2759; -.
DR Proteomes; UP000245320; Chromosome 5.
DR CDD; cd01269; PTB_TBC1D1_like; 1.
DR Gene3D; 1.10.10.2750; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR021785; DUF3350.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR PANTHER; PTHR47219; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR PANTHER; PTHR47219:SF18; TBC1 DOMAIN FAMILY MEMBER 1 ISOFORM X1; 1.
DR Pfam; PF11830; DUF3350; 1.
DR Pfam; PF00640; PID; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320}.
FT DOMAIN 164..243
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 762..956
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT REGION 79..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 635..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1107..1130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1009..1090
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 395..415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..510
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 515..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1130 AA; 127233 MW; 8A03C4C7315BB2DB CRC64;
MSPLFSWVAK VPEIISSIRQ AGKIARQDEL RCPSEFDDTF AKKFEVLFCG RVAVAHRKAP
PALIDECIEG FSHVSGGGFS SDQLRAAPQP PGDRERGPRP MRKSFSQPGL RSLAFRKEFQ
DAGLRSSSFF SSFEENDIEN HLISGHNIVQ PTDIEENRTM LFTIGQSEVY LISPDTKKIA
LEKNFKEISF CSQGIRHVDH FGFICRESSG GGGFHFVCYV FQCTNEALVD EIMMTLKQAF
TVAAVQQTAK ATAQLCEGCP LQGLHKLCER IEGMNSSKTK LELQKHLTTL TNQEQATIFE
EVQKLRPRNE QRENELIVSF LRCLYEEKQK VHVHIGEIKQ ASQIAAENTG SELPSSATRF
RLDMLKNKAK RSLTESLESI LSRGNKARGL QEHSASLDLD SSVSSTLSNT SKEPSVCEKE
AFPISESSFR LLGSSDDLSS DSESHAAEEP ALLSPQQGFR RRANTLSHIP VECQQPLQQA
QGSPGVSQRK LVRYHSVSTE TPHERNGNHP PVGESEGGSG QSSAAPPPRL TPSASSPNFF
KYLKHNPSGE QSGNAVPKSI SYRNALRKKL HSSSSVPNFL KFLAPVDENN TSDFMNTKRD
FESKASHLGD ASGTPVKTRR HSWRQQIFLR VATPQKACDS PGRHEDYSEL GELPPRSPLE
PVCEDGPFGP VPEEKKRTSR ELRELWQKAI LQQILLLRME KENQKLQASE NDLLNKRLKL
DYEEITPCLK EVTTVWEKML TTPGRSKIKF DMEKMHSAVG QGVPRHHRGE IWKFLAEQYH
LKHPFPSKQQ PKDTPYKELL KQLTSHQHAI LIDLGRTFPT HPYFSAQLGA GQLSLYNILK
AYSLLDQEVG YCQGLSFVAG ILLLHMGEEE AFNMLKFLMF DMGLRKQYRP DMIILQIQMY
QLSRLLHDYH RDLYNHLEEH EIGPSLYAAP WFLTVFASQF PLGFVARVFD MIFLQGSEVI
FKVALSLLGS HKPLILQHEN LETIVDFIKS TLPNLGLVQM EKTISQVFVM DISKQLQAYE
VEYHVLQEEL IDPSPLSDNQ RMDRLEKTNS SLRKQNLDLL EQLQVANGRI QSLEATIEKL
LTSESKLKQA TLALELERSA LLQTVERLQG QTAELGGPEP DPVPPEPAGH
//
