ID A0A2U4ASW9_TURTR Unreviewed; 885 AA.
AC A0A2U4ASW9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 07-OCT-2020, sequence version 2.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Zinc finger and BTB domain-containing protein 49 isoform X1 {ECO:0000313|RefSeq:XP_019784065.2};
GN Name=ZBTB49 {ECO:0000313|RefSeq:XP_019784065.2};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019784065.2};
RN [1] {ECO:0000313|RefSeq:XP_019784065.2}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_019784065.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR RefSeq; XP_019784065.2; XM_019928506.2.
DR AlphaFoldDB; A0A2U4ASW9; -.
DR InParanoid; A0A2U4ASW9; -.
DR OrthoDB; 5295767at2759; -.
DR Proteomes; UP000245320; Chromosome 5.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd18233; BTB_POZ_ZBTB49; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 7.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24394; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24394:SF45; ZINC FINGER PROTEIN 771; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00096; zf-C2H2; 6.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 7.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 149..215
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 519..546
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 547..574
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 575..602
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 603..630
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 631..658
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 659..686
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 687..714
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 292..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 400..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..486
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 885 AA; 98845 MW; 115F1EDD7C41740F CRC64;
MMSDEIFCIH IMASVSFRVK VKVLKRPCKA LRGLALCLSF PSLPLPSPWC QVLPLPWLQL
PTQLRLTLHD CQCFCSRSPG SFPFLPQVSA KVAPCQRGWR DEWMEVLPCG TSLIAVLWSP
GWWSMDPVAT HSCHLLQQLH EQRIQGLLCD CMLVVKGVCF KAHKNVLAAF SQYFRSLFQN
SSGQKNDVFH LDIKNVSGIG QILDFMYTSH LDLNQDNIQV MLDTAQCLQV QNVLNLCHTF
LKSAGVDQPP GLPCHSTFSL QSALTPDANC VISENYAPHL LQECSAGVQQ GRVVDESHSH
APPSVGLHTS TAETSKQAPD TLDGSCTELP FKQPNYYYKL RNLYSKQYYK QATCPSHERI
IKQPFTFSTS SDLHAAEHQP CAVGHAECVL ESSEHLPSNF LAQPLSEPTP DPEPDHTSQQ
PTRQMRLKKA IHLKKLNFLK SQKSAEQTSE PKSDDRLTKR IESASDHSVE KVNSQSAEEK
ESEELISSEN FNCMNEMERP EDTAALEDQS QTLQSQRQYA CELCGKPFKH PSNLELHKRS
HTGEKPFECN ICGKHFSQAG NLQTHLRRHS GEKPYICEIC GKRFAASGDV QRHIIIHSGE
KPHLCDICGR GFSNFSNLKE HKKTHTADKV FTCDECGKSF NMQRKLVKHR VRHTGERPYS
CSACGKCFGG SGDLRRHVRT HTGEKPYTCD ICNKCFTRSA VLRRHKKMHC RADDQGQDAL
EELTQAIETS DLEKSQSSDS FSQDVSLTLM PVSVKIPVHP VEEDSVAEFD SHCKFRSLVQ
SHGASEQEKL SLGPLKLAKP HVPQAQHQAY SYSGVEASAG TEPLQADGMA AIRSSLAALD
HHCADPLGSR ASAPAYRNSE GQFFSSMTLW GLAMKTLQNE SELDQ
//
