ID   A0A2U4AW23_TURTR        Unreviewed;      1138 AA.
AC   A0A2U4AW23;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   07-OCT-2020, sequence version 2.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=AP-4 complex subunit epsilon-1 isoform X1 {ECO:0000313|RefSeq:XP_019785004.2};
GN   Name=AP4E1 {ECO:0000313|RefSeq:XP_019785004.2};
OS   Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Delphinidae; Tursiops.
OX   NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019785004.2};
RN   [1] {ECO:0000313|RefSeq:XP_019785004.2}
RP   IDENTIFICATION.
RC   TISSUE=Spleen {ECO:0000313|RefSeq:XP_019785004.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_019785004.2; XM_019929445.2.
DR   AlphaFoldDB; A0A2U4AW23; -.
DR   STRING; 9739.ENSTTRP00000015941; -.
DR   InParanoid; A0A2U4AW23; -.
DR   OMA; ADNNMEI; -.
DR   OrthoDB; 25313at2759; -.
DR   Proteomes; UP000245320; Chromosome 2.
DR   GO; GO:0030124; C:AP-4 adaptor complex; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR017109; AP4_complex_esu.
DR   InterPro; IPR028269; AP4E1_C.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR   PANTHER; PTHR22780; ADAPTIN, ALPHA/GAMMA/EPSILON; 1.
DR   PANTHER; PTHR22780:SF13; AP-4 COMPLEX SUBUNIT EPSILON-1; 1.
DR   Pfam; PF01602; Adaptin_N; 1.
DR   Pfam; PF14807; AP4E_app_platf; 1.
DR   PIRSF; PIRSF037097; AP4_complex_epsilon; 1.
DR   SMART; SM01356; AP4E_app_platf; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   4: Predicted;
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          1033..1136
FT                   /note="AP-4 complex subunit epsilon-1 C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01356"
SQ   SEQUENCE   1138 AA;  127968 MW;  D0EB9505815DA994 CRC64;
     MSDIVEKTLT ALPGLFLQNQ SASGPAAAKA SFSSRLGGLV RGITALTSKH EEEKLIQQEL
     SNLKATVSAP TTTLKMMKEC MVRLIYCEML GYDASFGYIH AIKLAQQGNL LEKRVGYLAV
     SLFLHESHEL LLLLVNTVVK DLQSTNLVEV CMALTIVSQI FPREMIPAVL PLIEDKLQHS
     KEIIRRKAVL ALYKFYLIAP NQVQHIHIKF RKALCDRDVG VMAASLHIYL RMIKENSSAY
     KDLTGSFVTI LKQVVGGKLP VDFNYHSVPA PWLQIQLLRI LGLLGKDDQR TSELMYDVLD
     ESLRRAELNH NVTYAILFEC VHTVYSIYPK SELLEKAAKC IGKFVLSPKI NLKYLGLKAL
     TYVIQQDPTL ALQHQMTIIE CLDHPDPIIK RETLELLYRI TNAQNITVIV QKMLEYLHQS
     KEEYIIVNLV GKIAELAEKY APDNAWFIQT MNAVFSVGGD VMHPDIPNNF LRLLAEGFDD
     ETENQQLRLY AVQSYFTLLD VENVFYPQRF LQVMSWVLGE YSYLLDKETP EEVITKLYKL
     LRSDSISSET KAWIIAAVTK LTPQAHSSNI VERLIQEFTT SLDTCLRQHA FELKHLHENV
     KFMKGLLPVD KSCEDMVVDA SLSFLDGFVA EELSQGAAPY KPHHQRQEEK LSQEKVLSFE
     PYGLSFSSSG FSGRQSPAGI SLGSDISGNS TETGLKETNS LKLEGIKKLW GKEGYLPKKE
     SKTGDETEAL PVPQENIIME NVDQIITKND QSQALTQSKE EKEKQLLASS LFVGLGSEST
     INLLGKADTL SHKFRRKSKV KETKNGQTTT AQNMTCSSFS SSSNVAYEED YYLDHLQDRG
     DKEVKKFSLN SELLDSESLT ELPLVEKISN CRLSTPSLFA DNNMEVFHPP QSTAASVANE
     VSLAVSLLEE TTEHMHSDLI EVCNNETISV SSYKIWKDEC LLMVWSVFNK SASELKSANL
     EIAPAENFKI TEQPGCCLPV IEAESTKNFQ YSVQMEKPFT EGNLSGFINY QVMDTHSVQL
     EFSVNLSLLD FIRPLKISTE DFGKLWLSFA NDVKQNVKMS ESQAALPSTL KALQQELRLH
     VVDIIGNEGL LACQLLPSIP CLLHFRVHGD MLALWFRSSC STLPDYLLYQ CQKVMEGS
//