ID   A0A2U4AXI7_TURTR        Unreviewed;      1447 AA.
AC   A0A2U4AXI7;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Rapamycin-insensitive companion of mTOR isoform X6 {ECO:0000313|RefSeq:XP_019785677.1};
GN   Name=RICTOR {ECO:0000313|RefSeq:XP_019785677.1};
OS   Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Delphinidae; Tursiops.
OX   NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019785677.1};
RN   [1] {ECO:0000313|RefSeq:XP_019785677.1}
RP   IDENTIFICATION.
RC   TISSUE=Spleen {ECO:0000313|RefSeq:XP_019785677.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the RICTOR family.
CC       {ECO:0000256|ARBA:ARBA00008878}.
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DR   RefSeq; XP_019785677.1; XM_019930118.2.
DR   GeneID; 101320462; -.
DR   OrthoDB; 90320at2759; -.
DR   Proteomes; UP000245320; Chromosome 3.
DR   GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR   GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR028268; Pianissimo_fam.
DR   InterPro; IPR028267; Pianissimo_N.
DR   InterPro; IPR029453; Rictor_IV.
DR   InterPro; IPR029451; RICTOR_M.
DR   InterPro; IPR029259; RICTOR_phospho.
DR   InterPro; IPR029452; RICTOR_V.
DR   PANTHER; PTHR13298; CYTOSOLIC REGULATOR PIANISSIMO; 1.
DR   PANTHER; PTHR13298:SF11; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; 1.
DR   Pfam; PF14663; RasGEF_N_2; 1.
DR   Pfam; PF14666; RICTOR_M; 1.
DR   Pfam; PF14664; RICTOR_N; 1.
DR   Pfam; PF14665; RICTOR_phospho; 1.
DR   Pfam; PF14668; RICTOR_V; 1.
DR   SMART; SM01303; RasGEF_N_2; 1.
DR   SMART; SM01307; RICTOR_M; 1.
DR   SMART; SM01308; RICTOR_N; 1.
DR   SMART; SM01309; RICTOR_phospho; 1.
DR   SMART; SM01310; RICTOR_V; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245320}.
FT   DOMAIN          1..154
FT                   /note="Rapamycin-insensitive companion of mTOR N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01308"
FT   DOMAIN          238..457
FT                   /note="Rapamycin-insensitive companion of mTOR middle"
FT                   /evidence="ECO:0000259|SMART:SM01307"
FT   DOMAIN          635..707
FT                   /note="Rapamycin-insensitive companion of mTOR"
FT                   /evidence="ECO:0000259|SMART:SM01310"
FT   REGION          736..759
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          815..846
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          907..963
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          988..1013
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        736..757
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        918..963
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1447 AA;  162540 MW;  44F859D2DBE670BB CRC64;
     MGIIATFRSW AGIINLCKPG NSGIQSLIGV LCIPNMEIRR GLLEVLYDIF RLPLPVVTEE
     FIEALLSVDP GRFQDSWRLS DGFVAAEAKT ILPHRARSRP DLMDNYLALI LSAFIRNGLL
     EGLVEVITNS DDHISVRATI LLGELLHMAN TILPHSHSHH LHCLPTLMNM AASFDIPKEK
     RLRASAALNC LKRFHEMKKR GPKPYSLHLD HIIQKAIATH QKRDQYLRVQ KDIFVLKDTE
     EALLMNLRDS QVLQHKENLE WNWNLIGTIL KWPNVNLRNY KDEQLHRFVR RLLYFYKPSS
     KLYANLDLDF AKSKQLTVVG CQFTEFLLES EEDGQGYLED LVKDIVQWLN ASSGMKPERS
     LQNNGLLTTL SQHYFLFIGT LSCHPHGVKM LEKCSVFQCL LNLCSLKNQD HLLKLTVSSL
     DYSRDGLARV ILSKILTAAT DACRLYATKH LRVLLRANVE FFNNWGIELL VTQLHDKNKT
     ISSEALDILD EACEDKANLH ALIQMKPALS HLGDKGLLLL LRFLSIPKGF SYLNERGYIA
     KQLEKWHKEY NSKYVDLIEE QLNEALTTYR KPIDGDNYVR RSNQRLQRPH VYLPVHLYGQ
     LVHHKTGCHL LEVQNIITEL CHSVRTPDLD KWEEIKKLKA SLWALGNIGS SNWGLNLLQE
     ENVIPDILKL AKQCEVLSIR GTCVYVLGLI AKTKQGCDIL KCHNWDAVRH SRKHLWPVVP
     DDVEQLCNEL SSVPSTLSLN SESTSSRHNS ESESAPSSMF IMEDDRFGSS STSTFFLDIN
     EDAEPAFYDR SGPMKDKNSF PFFASSKLVK NRILNSLTLP NKKHRSSSDP KGGKLSSENK
     TSNRRIRTLT EPSVDFNHSD DFTPISTVQK TLQLETSFVG NKHIEDTGST PSIGENDLKF
     TKSLGTENHR ENTSRERLVV ESSASSHMKI RSQSFNTDTT TSGISSMSSS PSRETVGVDA
     TTVDTDCGSM STVVSTKTVK TSHYLTPQSS HLSLSKSNSV SLVPPGSSHT LPRRAQSLKA
     PSIATIKSLA DCNFSYTSSR DAFGYATLKR LQQQRMHPSL SHSEALASPA KDVLFTDTIT
     MKANSFESRL TPSRIDFKKK HVGGIRSLRP TITNNLFRFM KALSYASLDK EDLLSPINQN
     TLQRSSSVRS MVSSATYGSS DDYIGLALPV DINDIFQVKD IPYFQAKNIP PHDDRGARVF
     AHDAGGLPSG TGGLVKNSFH LLRQQMSLTE IMNSIHSDAS LFLESTEDTG LQEHTDDNCL
     YCVCIEILGF QPSNQLSAIC SHSDLQDIPY SDWCEQTIHN PLEVVPSKFS GISGCSDGVS
     QEGSASSTKS TELLLGVKTI PDDTPMCRIL LRKEVLRLVI NLSSSVSTKC HETGLLTIKE
     KYPQTFDDIC LYSEVSHLLS HCTFRLPCRR FIQELFQDVQ FLQMHEEAEA VLATPPKRPI
     VDTSVES
//