ID A0A2U4B0T6_TURTR Unreviewed; 414 AA.
AC A0A2U4B0T6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Interleukin-18 receptor 1 isoform X3 {ECO:0000313|RefSeq:XP_019786817.1};
GN Name=IL18R1 {ECO:0000313|RefSeq:XP_019786817.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019786817.1};
RN [1] {ECO:0000313|RefSeq:XP_019786817.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_019786817.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the interleukin-1 receptor family.
CC {ECO:0000256|ARBA:ARBA00009752}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_019786817.1; XM_019931258.2.
DR AlphaFoldDB; A0A2U4B0T6; -.
DR GeneID; 101331669; -.
DR OrthoDB; 4322253at2759; -.
DR Proteomes; UP000245320; Chromosome 14.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR015621; IL-1_rcpt_fam.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11890; INTERLEUKIN-1 RECEPTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11890:SF6; INTERLEUKIN-18 RECEPTOR 1; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR01537; INTRLKN1R1F.
DR SMART; SM00409; IG; 2.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS50104; TIR; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Receptor {ECO:0000313|RefSeq:XP_019786817.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 93..185
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 246..393
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 414 AA; 47783 MW; F1C01CF969A43B0D CRC64;
MSKSVEVKKS LQIACEHSYY QKLVNRTLLY KNCEKIQNNR NPFLKKNAEF KDQGYYTCMF
FLLRNGKLFN VTKTFNITIV GDNSNIIPAL LGPKLTHVKV ELGKDVQLNC SALLNEKDVI
YWNIWKKNGK DPNVHEEEGT RIRTSEGKWL ASKILRIETV NENNLNFSYN CTAASEGGID
TKSFILLKKE DPVDIPGHIF TRGMIVAVLI SVVIVCLVTV CAIYRVDLVL FYRHFLGRDE
TLTDGKTYDA FVSYLKECRP ENGEEHTFAV EILPRVLEKH FGYKLCIFER DVVPGRAVVD
EIHSLIEKSR RLIIVLSKSY MSNEVRYELE SGLHEALVER KIKIILIEFT PIGDFTFLPQ
SLKLLKSHRV LKWQADKSLS YNSRFWKNLL YLMPAKAVKP YREEAEVLPV FSQP
//
