ID A0A2U4B362_TURTR Unreviewed; 1282 AA.
AC A0A2U4B362;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=DENN domain-containing protein 3 isoform X5 {ECO:0000313|RefSeq:XP_019787509.1};
GN Name=DENND3 {ECO:0000313|RefSeq:XP_019787509.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019787509.1};
RN [1] {ECO:0000313|RefSeq:XP_019787509.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_019787509.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_019787509.1; XM_019931950.2.
DR STRING; 9739.ENSTTRP00000007126; -.
DR GeneID; 101322190; -.
DR OrthoDB; 5354449at2759; -.
DR Proteomes; UP000245320; Chromosome 17.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.200; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12296:SF21; DENN DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR12296; DENN DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF02141; DENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS50211; DENN; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320}.
FT DOMAIN 76..508
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT REGION 79..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1282 AA; 143717 MW; D548B5DF782C4B38 CRC64;
MAEAGPQYLA LPSGLLELCA LLGAPRDSLR GPEQVAQKKG VKSLSSLDPE VLSVFVPPFV
TKEDSQPAGV NCVTLGKTRR RSFRKKRERP KAEPSKGHPG GPRGQDPEDV GIPNGVDLLA
LPQLCFPGGV CVASEPKEDC VHFLVLTDVC GNRTHGVVAQ YYRPLHDEYC FYNGKMRWEA
SGLGRSAAGC FVPFAVCVVS RFPYYNALKD CLSCLLTHLK ICKDFEVDNH IKDFAAKLSL
IPSPPPGPLH LVLNMKPLQI VFPSRADPES PLIDLDLHLP LLCFRPEKVL QILTCLLTEQ
HVVFFSSSWA LLTLVAECFM AYLHPLQWQH TFVPILSRQM LDFVMAPTSF LMGCHLDHFE
EVSKEADGLI LINIDTGSIT FSNDEDVDVP DIPLLAAQTF IQRVQSLQMH RELDLAHLCA
STDLNEGRAC QRAWQQRLNC QIQQITLQLL VCIFRGVKNH LNYEHRVFNS EEFLKTRAPG
DQQFYKQVLD TYMFHAFLKA RLSRRMDAFA QMDLCTQSEE DRIDGMLLSP RRPTVEKMAS
RKPSAPHGAH RRMVVSMPNL QDIAVPELPP RNSSLRKMRT EDCGGSHTVL DVPPKLTYTF
KIPEIHFPLV GQCVQAFHAD CVAQLSKAMD SLAPENSVLL ARYFYLRGLV QLMQGQLLGA
LLDFQSLYKT DVRIFPADLV QRTVKSLSAP ERAQAERTPE LRRLISEVVD KPEDAPKADD
RVKNFELPKK HMQLDDFVKR VQESGIVKDA GIIHRLFEAL TVGHQKQIDP ETFKDFYNCW
KEAEAEAQGV NLPFSVTEQL DKNECVYKLS SSVKTNRGVG KIAMTQKRLF LLTEGRPGYV
EISTFRNIEE VRNTTVAFLL LRIPTLKIKV LSKKEVFEAN LKTECDLWHL MVKEMWAGKK
LADDHKDPQY VQQALTHVLL MDAVVGALQS PGAIYAASKL SYFDKMKNEM PMAVPKTTSE
TLKHKINPSA GETLPRAIDV LLYTPGHLDP AEKVEDAHPK LWCALNEGKV VVFDASSWTV
HQHCFKVGTS KLNCMVMAEQ TQVWVGSEDS VIYIINVHSM SCNKQLTDHR SSVTGLVVQD
RAQAPSTVYS CSVDGTVLAW NASSLQVTSR FQLPGDGLLA IRLHGGRLWC CTGNSIVVVT
TAGFLHQELK IGENFKEIST SFLGFQLMPE QEQLWAACAG YDDIYVWSLQ DLAQPPQRIH
LQDCSRIHCM IQVKKQIWVG GTGLSQGRSK GKIYVIDAER KTVEKELVAH MDTVNTLCSA
EDRYVLSGSG RDEGKIAIWK VE
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