ID A0A2U4B9D9_TURTR Unreviewed; 273 AA.
AC A0A2U4B9D9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=SPRY domain-containing SOCS box protein 4 isoform X2 {ECO:0000313|RefSeq:XP_019789679.1};
GN Name=SPSB4 {ECO:0000313|RefSeq:XP_019789679.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019789679.1};
RN [1] {ECO:0000313|RefSeq:XP_019789679.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_019789679.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the SPSB family.
CC {ECO:0000256|ARBA:ARBA00010910}.
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DR RefSeq; XP_019789679.1; XM_019934120.2.
DR AlphaFoldDB; A0A2U4B9D9; -.
DR STRING; 9739.ENSTTRP00000003085; -.
DR GeneID; 101335396; -.
DR OrthoDB; 65989at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000245320; Chromosome 4.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03718; SOCS_SSB1_4; 1.
DR CDD; cd12906; SPRY_SOCS1-2-4; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR12245; SPRY DOMAIN CONTAINING SOCS BOX PROTEIN; 1.
DR PANTHER; PTHR12245:SF3; SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000245320}.
FT DOMAIN 34..233
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 233..273
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 273 AA; 30228 MW; 421CB58A3907F86C CRC64;
MGQKLSGSLK SVEVREPALR PAKRELRGAE PGRPARLDQL LDMPAAGLAV QLRHAWNPED
RSLNVFVKDD DRLTFHRHPV AQSTDGIRGK VGHARGLHAW QIHWPARQRG THAVVGVATA
RAPLHSVGYT ALVGSDAESW GWDLGRSRLY HDGKNRPGVA YPAFLGPDEA FALPDSLLVV
LDMDEGTLSF VVDGQYLGVA FRGLKGKKLY PVVSAVWGHC EVTMRYINGL DPEPLPLMDL
CRRCIRLALG RQRLQDIGSL PLPQSLKNYL QYQ
//
