ID A0A2U4BYG2_TURTR Unreviewed; 482 AA.
AC A0A2U4BYG2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 07-OCT-2020, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Zinc finger protein 140 isoform X1 {ECO:0000313|RefSeq:XP_019798247.2};
GN Name=ZNF140 {ECO:0000313|RefSeq:XP_019798247.2};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019798247.2};
RN [1] {ECO:0000313|RefSeq:XP_019798247.2}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_019798247.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_019798247.2; XM_019942688.2.
DR AlphaFoldDB; A0A2U4BYG2; -.
DR InParanoid; A0A2U4BYG2; -.
DR OrthoDB; 3823881at2759; -.
DR Proteomes; UP000245320; Chromosome 13.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF140; ZINC FINGER PROTEIN 726; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 9.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 16..88
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 178..205
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 206..233
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 234..261
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 262..289
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 290..317
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 318..345
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 346..373
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 374..401
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 402..429
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 430..457
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 482 AA; 55542 MW; F98D0A0CCB8F3F94 CRC64;
MGAGCADVCV SFQGSVTFRD VAVDFSREEW EWLQPAQRDL YRHVMLENYG HLVSLAGLNI
SKPHVVSLLE QGKEPWLGKD ASRGLFSASE SNGEIKEFSP KNVIYEDDSS QYLIRSSNLS
FERFLSQGLE YSNFKEGWKC EGDTEMLQGN QGYVRQVTVS HQEALSQHMN VSTVERPYGC
HECGKTFSRR FSLVLHQRTH TGEKPYVCKE CGKTFSQISN LVKHQMIHTG KKPHECKDCN
KTFSYLSFLI EHQRTHTGEK PYECTECGKA FSRASNLTRH QRIHIGKKQY VCRRCGKAFS
SGSELIRHQI THTGEKPYEC IECGKAFRRS SHLSRHQSVH TSKTPYECNE CSKAFRCHSF
LIKHQRIHAG EKLYECDECG KVFTWHASLV QHMRIHTGEK PYACTECDKT FSRSFSLILH
QITHTGEKPY VCKVCNKSFS WSSNLTKHQR THTLENTYEY ENSFNYHSFL AEHQGIHTVE
KT
//
