ID   A0A2U4C2D6_TURTR        Unreviewed;       919 AA.
AC   A0A2U4C2D6;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1 {ECO:0000313|RefSeq:XP_019799598.1};
GN   Name=NFATC2 {ECO:0000313|RefSeq:XP_019799598.1};
OS   Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Delphinidae; Tursiops.
OX   NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_019799598.1};
RN   [1] {ECO:0000313|RefSeq:XP_019799598.1}
RP   IDENTIFICATION.
RC   TISSUE=Spleen {ECO:0000313|RefSeq:XP_019799598.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_019799598.1; XM_019944039.2.
DR   AlphaFoldDB; A0A2U4C2D6; -.
DR   STRING; 9739.ENSTTRP00000007313; -.
DR   GeneID; 101336477; -.
DR   InParanoid; A0A2U4C2D6; -.
DR   OrthoDB; 5405363at2759; -.
DR   Proteomes; UP000245320; Chromosome 15.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd01178; IPT_NFAT; 1.
DR   CDD; cd07881; RHD-n_NFAT; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002909; IPT_dom.
DR   InterPro; IPR008366; NFAT.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR032397; RHD_dimer.
DR   InterPro; IPR011539; RHD_DNA_bind_dom.
DR   InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR   PANTHER; PTHR12533; NFAT; 1.
DR   PANTHER; PTHR12533:SF4; NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2; 1.
DR   Pfam; PF16179; RHD_dimer; 1.
DR   Pfam; PF00554; RHD_DNA_bind; 1.
DR   PRINTS; PR01789; NUCFACTORATC.
DR   SMART; SM00429; IPT; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 1.
DR   PROSITE; PS50254; REL_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245320}.
FT   DOMAIN          386..568
FT                   /note="RHD"
FT                   /evidence="ECO:0000259|PROSITE:PS50254"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          45..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          195..292
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          865..888
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   919 AA;  99631 MW;  CC39692096607978 CRC64;
     MDAQEPQPDP DGGGAPGHEP GGSPQDEFDF SILFDYDYLN PIEEEPNAHK VASPPSGLAY
     PDDVLDYGLK PYSPLDSLSG EPPHRLGEPD RVGPQNFLCP AKPAGASGLS PRIEITPSHE
     LMQSGGPFRM RDTGLVVEQP PLPGVAASPR FTLPVPGFEG YREPLCLSPA SSGSSASFIS
     DTFSPYTSPC VSPNNGGPDD LCPQFQNIPA HYSPRTSPIM SPRTGLAEDS CLGRHSPVPR
     PASRSSSPGT KRRHSCAGAL VAPLPGASPQ RSRSPSPQPR DDGAPAGYPP AAGSAVLMDA
     LNSLAADSPC GIPPKMWKTS PDPSPVSSAP SKAGLPRHIY PAVEFLGPCE QEERRNSAPE
     SILLVPPTWP KQLVPAIPIC SIPVTASLPP LEWPLSHQSG SYELRIEVQP KPHHRAHYET
     EGSRGAVKAP TGGHPVVQLH GYMENKPLGL QIFIGTADER ILKPHAFYQV HRITGKTVTT
     TSYEKIVGNT KVLEIPLEPK NNMRATIDCA GILKLRNADI ELRKGETDIG RKNTRVRLVF
     RVHIPESSGR IVSLQIASNP IECSQRSAHE LPMVERQDID SCLVYGGQQM ILTGQNFTAE
     SKVVFTEKTT DGQQIWEMEA TVDKDKSQPN MLFVEIPEYR NKHIRTSVKV NFYVINGKRK
     RSQPQHFTYH PVPAIKTEPT DEYDPTLICS PAHGGLGSQP YYPQHPMVAE SPSCLVATMA
     PCQQFRSGLS SPDTRYQQQN PAAVLYQRSK SLSPSLLGYQ QPALMAAPLS LADAHRSVLV
     HAGSQGQSSA LLHSSPANQQ ASPVIHYSPT NQQLRCGSHQ EFQHIVYCEN FAPGTTRPGP
     PPVSQGQRLS PGSYPTVIQQ QNATSQRAAK NGPPVSDQKE VLPAGVTIKQ EQNLDQTYLD
     DVNEIIRKEF SGPPARNQT
//